Results 201 to 210 of about 680,559 (291)

Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing. [PDF]

EMBO Mol Med
Haas J, Schudy S, Rauscher B, Muñoz Verdú A, Roßkopf S, Reich C, Donmez Yalcin G, Yalcin A, Seeger T, Dieterich C, Taft MH, Freichel M, Grimm D, Manstein D, Backs J, Frey N, Steinmetz L, Meder B.   +17 more
europepmc   +1 more source

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Landscape of Somatic and Age-Related Pathogenic Structural Variations in Hepatocellular Carcinoma Revealed by Long-Read Sequencing. [PDF]

MedComm (2020)
Wei Z, Cao Y, Liu H, Liu M, Zhang B, Ying J, Cai J, Bi X, Zhao J, Zhou J, Li Z, Huang Z, Liu J, Lv X, Luo Z, Wei Z, Zhang X, Yang Y, Deng Y, Yin Y, Chen J, Liang J, Wang X, Zhang Y, Zhao H.   +24 more
europepmc   +1 more source

Digital Actuation Control of Soft Robotic Origami With Self‐Folding Liquid Crystal Elastomer Hinges

Advanced Functional Materials, EarlyView.
Self‐folding soft‐rigid hybrid robotic origami is enabled by liquid crystal elastomer actuators with embedded Joule heating and closed‐loop digital control. Digitally addressable hinges provide reversible and programmable transitions between distinct folded states while maintaining actuation performance at high cycle counts (over 1500).
David C. Bershadsky, Tuo Zhao, Glaucio H. Paulino, Emily C. Davidson   +3 more
wiley   +1 more source

Clinical Long-Read Sequencing Test for Genetic Disease Diagnosis.

JAMA Pediatr
Thiffault I, Farrow E, Barrett C, Scott M, Ross A, Means JC, Cheung WA, Johnson AF, Koseva B, McLennan R, Grundberg E, Bi C, Schwendinger-Schreck C, Yoo B, Johnston JJ, Del Viso F, Paolillo V, Herriges J, Zhang L, Gibson M, Cohen ASA, Alaimo J, Saunders CJ, Pastinen T.   +23 more
europepmc   +1 more source

Imaging of Biphoton States: Fundamentals and Applications

Advanced Functional Materials, EarlyView.
Quantum states of two photons exhibit a rich polarization and spatial structure, which provides a fundamental resource of strongly correlated and entangled states. This review analyzes the physics of these intriguing properties and explores the various techniques and technologies available to measure them, including the state of the art of their ...
Alessio D'Errico, Ebrahim Karimi
wiley   +1 more source

Expanding the genetic landscape of inherited metabolic diseases using long-read sequencing and transcriptomic profiling. [PDF]

Eur J Hum Genet
Soriano-Sexto A, Sánchez-Lijarcio O, Beccari L, Castejón-Fernández N, Leal F, Alcaide P, de la Morena-Barrio B, Bahíllo-Curieses MDP, Correcher P, Hencke-Tresbach R, López L, Martín-Hernández E, Yahyaoui R, Ugarte M, Rodríguez-Pombo P, Pérez B.   +15 more
europepmc   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source