Results 191 to 200 of about 3,183,091 (359)

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

Regulation of Ischemic Long-Term Potentiation in GluN2B and FKBP51 Underlying Cathodal Direct Current Stimulation. [PDF]

Neurochem Res
Lee CW, Tang CW, Chang CH, Chia CM, Hsieh TH, Chi H, Lin HC.   +6 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

A Novel NLRP3 Inhibitor AMS-17 Rescues Deficits in Long-Term Potentiation Following Mild Traumatic Brain Injury in Adult C57Bl/6 Mice. [PDF]

Hippocampus
Eyolfson E, Bettio L, Brand J, Gupta NK, Hamer E, Salas R, Kulkarni A, Christie BR.   +7 more
europepmc   +1 more source

Long-Term Potentiation and Closed-Loop Learning in Paired Brain Organoids for CNS Drug Discovery [PDF]

Corey M. Rountree, Eva Schmidt, Nicholas Coungeris, Victoria Alstat, Andrew S. LaCroix, Megan A. Morris, Michael J. Moore, J. Lowry Curley   +7 more
openalex   +1 more source

An Ultrathin, Cyano‐Functionalized Copolymeric Memristor by iCVD Process for Driving Convolutional Neural Networks of High‐Resolution Images

Advanced Science, EarlyView.
Two‐terminal polymer memristors based on cyano‐functionalized copolymer films are developed via a solvent‐free, initiated chemical vapor deposition (iCVD) process for high‐resolution image classification. Molecularly engineered p(CEA‐co‐DEGDVE) films enable stable, linear, and symmetric conductance modulation, supporting multi‐level weight mapping in ...
Ji In Kim, Minsu So, Woo Jin Wang, Taehoon Kim, Eun Su Jeong, Kyumin Sim, Hamin Park, Sung Kyu Kim, Yong Goo Shin, Junhwan Choi, Min Ju Kim   +10 more
wiley   +1 more source

Differential Astrocyte-Supplied NMDAR Co-Agonist for CA1 Versus Dentate Gyrus Long-Term Potentiation. [PDF]

Hippocampus
Sateesh S, Abraham WC.
europepmc   +1 more source

Synaptic inhibition regulates associative interactions between afferents during the induction of long-term potentiation and depression.

, 1993
Richard A. Tomasulo, J.J. Ramirez, Oswald Steward   +2 more
openalex   +2 more sources

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation. [PDF]

Elife
Wang J, Nishiyama J, Parra-Bueno P, Okaz E, Oz G, Liu X, Watabe T, Suponitsky-Kroyter I, McGraw TE, Szatmari EM, Yasuda R.   +10 more
europepmc   +1 more source