Results 191 to 200 of about 78,829 (257)

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

Median raphe glutamatergic neuron-mediated enhancement of GABAergic transmission and suppression of long-term potentiation in the hippocampus. [PDF]

Heliyon
Stinson HE, Ninan I.
europepmc   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. [PDF]

Nat Commun
Sayegh FJP, Mouledous L, Macri C, Pi Macedo J, Lejards C, Rampon C, Verret L, Dahan L.   +7 more
europepmc   +1 more source

Impaired Hippocampal Long-Term Potentiation and Memory Deficits upon Haploinsufficiency of MDGA1 Can Be Rescued by Acute Administration of D-Cycloserine. [PDF]

Int J Mol Sci
Ojima D, Tominaga Y, Kubota T, Tada A, Takahashi H, Kishimoto Y, Tominaga T, Yamamoto T.   +7 more
europepmc   +1 more source

Reflecting on 50 years of long-term potentiation: Insights from the Royal Society's LTP50 conference. [PDF]

Brain Neurosci Adv
Mitchell-Heggs R, Tse D.
europepmc   +1 more source

Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins. [PDF]

Philos Trans R Soc Lond B Biol Sci
Ondrejcak T, Klyubin I, Hu NW, Yang Y, Zhang Q, Rodriguez BJ, Rowan MJ.   +6 more
europepmc   +1 more source

The Expression of Neurodegeneration-Related Genes in the Hippocampus of Hypothyroid Rats Following Long-Term Potentiation. [PDF]

Eurasian J Med
Altunkaya M, Babur E, Barutçu Ö, Süer C, Dursun N.   +4 more
europepmc   +1 more source

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Long-Term Potentiation

Annual Review of Neuroscience, 1987
History and Definition In 1973, two reports appeared in the Journal of Physiology that described a long-term potentiation (L TP) of synaptic transmission at a monosynaptic junction in the mammalian eNS. These two papers, one dealing with the anesthetized rabbit preparation (Bliss & L0mo 1973) and the other dealing with the unanesthetized rabbit (Bliss &
T J, Teyler, P, DiScenna
openaire   +3 more sources