Results 191 to 200 of about 81,804 (294)

Theory for Characterization of Hippocampal Long-Term Potentiation Induced by Time-Structured Stimuli [PDF]

, 1997
Masami Tatsuno, Yôji Aizawa
openalex   +1 more source

Oral Exposure to Food‐Grade Nanoparticles Poses a Risk of Alzheimer's Disease‐Like Symptoms by Triggering Autophagy Defects in Neurons

Advanced Science, EarlyView.
Three food‐grade nanomaterials induce dysregulated RyR‐Ca2+ signaling through epigenetic modifications. This dysregulation impairs the autophagic clearance process, ultimately leading to abnormal Aβ deposition and increase phosphorylated tau levels.
Jiaxin Shang, Jun Yan, He Lou, Xuanxi Jiang, Ziyue Wang, Yue Gao, Xiaohui Fan, Xiaoyan Lu   +7 more
wiley   +1 more source

A hyper-activatable CAMK2A variant associated with intellectual disability causes exaggerated long-term potentiation and learning impairments. [PDF]

Transl Psychiatry
Pan M, Liu PW, Ozawa Y, Arima-Yoshida F, Dong G, Sawahata M, Mori D, Nagase M, Fujii H, Ueda S, Yabuuchi Y, Liu X, Narita H, Konno A, Hirai H, Ozaki N, Yamada K, Kidokoro H, Bito H, Mizoguchi H, M Watabe A, Horigane SI, Takemoto-Kimura S.   +22 more
europepmc   +1 more source

Layer‐specific NO dependence of long‐term potentiation and biased NO release in layer V in the rat auditory cortex

, 1998
Hidemitsu Wakatsuki, Hiroshi Gomi, Masaharu Kudoh, Shinji Kimura, Kota Takahashi, Masayuki Takeda, Katsuei Shibuki   +6 more
openalex   +2 more sources

A Novel Zinc(II) Complex for Sonodynamic Therapy Induces Pyroptosis of Breast Cancer Cells and Enhances Anti‐Tumor Immune Response

Advanced Science, EarlyView.
Although Zinc(II) complexes are effective in photodynamic therapy, their efficacy is limited by the poor tissue penetration of light. This work introduces a novel zinc(II) complex for sonodynamic therapy. Under ultrasound activation, it generates substantial singlet oxygen, induces pyroptosis in breast cancer cells, and promotes anti‐tumor immune ...
Sijie Wen, Dongsheng Tang, Lingpu Zhang, Hanchen Zhang, Zheng Cao, Kong Wai Tan, Xiaojun Wang, Haihua Xiao, Kun Shang   +8 more
wiley   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Long-term potentiation: 50 years on: past, present and future. [PDF]

Philos Trans R Soc Lond B Biol Sci
Abraham WC, Bliss TVP, Collingridge GL, Morris RGM.   +3 more
europepmc   +1 more source

Repurposing Cardiac Glycosides to Potentiate CD47 Blockade through Calreticulin‐mediated Phagocytic Effects for Lung Cancer Treatment

Advanced Science, EarlyView.
Repurposing cardiac glycosides (CGs) significantly strengthens the efficacy of anti‐CD47 antibody for lung cancer treatment by boosting macrophage phagocytosis. This novel combination blocks the “don't eat me” signal and increases dual “eat‐me” signals, Fc‐FcγR and cell surface expression of calreticulin (ecto‐CRT).
Zi‐Han Ye, Wei‐Bang Yu, Mu‐Yang Huang, Yan‐Yan Chen, Le‐Le Zhang, Chung‐Hang Leung, Xiao‐Lei Zhang, Zhenghai Tang, Ting Li, Jin‐Jian Lu   +9 more
wiley   +1 more source

Inhibition of hippocampal interleukin-6 receptor-evoked signalling normalises long-term potentiation in dystrophin-deficient mdx mice. [PDF]

Brain Behav Immun Health
Stephenson KA, Barron A, Rae MG, O'Malley D.   +3 more
europepmc   +1 more source

Long-term potentiation increases tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit 2B in rat dentate gyrus in vivo.

, 1996
Kobi Rosenblum, Yadin Dudai, Gal Richter‐Levin   +2 more
openalex   +1 more source