Results 201 to 210 of about 80,618 (294)

Interference with glutamate antiporter system x_c ^- enables post-hypoxic long-term potentiation in hippocampus. [PDF]

Exp Physiol
Heit BS, Chu A, McRay A, Richmond JE, Heckman CJ, Larson J.   +5 more
europepmc   +1 more source

Nanoshield‐Assisted Viral Gene Therapy with Induction of Non‐Apoptotic Cell Death and Durable Antitumor Immunity

Advanced Science, EarlyView.
A novel hybrid gene delivery platform combines adeno‐associated virus (AAV)‐mediated receptor‐interacting kinase 3 (RIPK3) expression with manganese dioxide‐polyethyleneimine (MnO2−PEI) nanoshield to induce necroptosis, ferroptosis, and immunogenic cell death, effectively reprogramming the tumor microenvironment.
Soo‐Hwan Lee, Yunkyeong Cho, Seunghwan Bang, Daeun Sung, Jahyun Koo, Seoyoung Kim, Youngil Koh, Hojun Kim, Hyojin Lee   +8 more
wiley   +1 more source

Interplay of hippocampal long-term potentiation and long-term depression in enabling memory representations. [PDF]

Philos Trans R Soc Lond B Biol Sci
Hagena H, Manahan-Vaughan D.
europepmc   +1 more source

Lipid‐Based Nanoparticles in Cancer Therapy: Advances in Targeted Drug Delivery and Therapeutic Potential for Renal Cell Carcinoma

Advanced Science, EarlyView.
This review explores the transformative potential of lipid‐based nanoparticles (LNPs) in renal cell carcinoma (RCC) therapy. It systematically analyzes six LNP platforms‐from liposomes to hybrid nanoparticles‐highlighting their unique advantages in targeted drug delivery, resistance reversal, and immunomodulation.
Wei Yao, Yuhe Lin, Yang Weng, Yan Wu, Lufeng Zheng, Donghan Zheng, Qi Xi, Jingying Zhao   +7 more
wiley   +1 more source

Rapid and local neuroestrogen synthesis supports long-term potentiation of hippocampal Schaffer collaterals-cornu ammonis 1 synapse in ovariectomized mice. [PDF]

J Neuroendocrinol
Maroteaux MJ, Noccioli CT, Daniel JM, Schrader LA.   +3 more
europepmc   +1 more source

Long-term potentiation involves increases in the probability of neurotransmitter release

, 1997
Paul E. Schulz
openalex   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

Advanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, Rong Ye, Yuanchao Xue, Huiyun Wang, Musheng Zeng, Ming Yang, Huaiqiang Ju, Chengzhi Gao, Guangming Zhou, Qi Zhang, Qian Zhang, Geng Qin, Yuanfeng Li, Yahui Wang, Aiqing Yang, Anfeng Si, Qingfeng Song, Fuchu He, Pengbo Cao, Gangqiao Zhou   +28 more
wiley   +1 more source

Developmental ethanol exposure produces deficits in long-term potentiation in vivo that persist following postnatal choline supplementation. [PDF]

Alcohol Clin Exp Res (Hoboken)
Titterness AK, Gräfe EL, Acosta C, Rodriguez C, Thomas JD, Christie BR.   +5 more
europepmc   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Median raphe glutamatergic neuron-mediated enhancement of GABAergic transmission and suppression of long-term potentiation in the hippocampus. [PDF]

Heliyon
Stinson HE, Ninan I.
europepmc   +1 more source