Results 221 to 230 of about 81,804 (294)

Median raphe glutamatergic neuron-mediated enhancement of GABAergic transmission and suppression of long-term potentiation in the hippocampus. [PDF]

Heliyon
Stinson HE, Ninan I.
europepmc   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Integrin‐Piezo1 Axis Drives ECM Remodeling and Invasion of 3D Breast Epithelium

Advanced Science, EarlyView.
Mechanical stiffening of the extracellular matrix around mature mammary acini induces sequential remodeling phases. An early response disrupts the basement membrane and promotes fibronectin secretion, followed by delayed invasion with matrix reorganization and proliferation.
Kabilan Sakthivel, Anna Kotowska, Zhimeng Fan, Ellen Juel Portner, Catherine Merry, Pontus Nordenfelt, Adam Cohen Simonsen, Amanda J. Wright, Vinay S Swaminathan   +8 more
wiley   +1 more source

Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. [PDF]

Nat Commun
Sayegh FJP, Mouledous L, Macri C, Pi Macedo J, Lejards C, Rampon C, Verret L, Dahan L.   +7 more
europepmc   +1 more source

Changes in activities of MAP kinase and CaM kinase II in the induction of hippocampal long-term potentiation

, 1998
Jie Liu, Kohji Fukunaga, Katsuhide Nishi, Eishichi Miyamoto   +3 more
openalex   +1 more source

A Floating‐Gate Photoelectric Synaptic Transistor Utilizing BP/POx/WSe2 Heterostructure for Neuromorphic Visual Processing

Advanced Science, EarlyView.
In this paper, a novel floating gate transistor (BP/POx/WSe2) is developed, which enables rich synaptic functionality under optoelectronic conditions and can mimic human visual memory. By introducing a two‐path convolutional neural network that synergistically fuses optical and electronic inputs, it can achieve efficient feature extraction and weight ...
Yuxuan Zeng, Wenxing Lv, Zehai Hou, Weihua Huang, Zhipeng Yu, Zishuo Han, Rongbin Zhan, Tianle Zeng, Yawen Luo, Yu Lin, Weiming Lv, Bin Fang, Zhongming Zeng, Lianbo Guo   +13 more
wiley   +1 more source

Impaired Hippocampal Long-Term Potentiation and Memory Deficits upon Haploinsufficiency of MDGA1 Can Be Rescued by Acute Administration of D-Cycloserine. [PDF]

Int J Mol Sci
Ojima D, Tominaga Y, Kubota T, Tada A, Takahashi H, Kishimoto Y, Tominaga T, Yamamoto T.   +7 more
europepmc   +1 more source

The long-term potentiation in perforant pathdentate gyrus synapses is related with contextual fear conditioning

, 1999
Kiyoshi Mori, Hiroko Togashi, Machiko Matsumoto, Mitsuhiro Yoshioka   +3 more
openalex   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source