Results 41 to 50 of about 82,808 (286)

Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiationin Vivo [PDF]

, 2023
Tomáš Ondrejčák, Igor Klyubin, Neng‐Wei Hu, Tiernan T. O’Malley, Grant T. Corbett, Róisín Winters, Michael S. Perkinton, Andy Billinton, Jack Prenderville, Dominic M. Walsh, Michael J. Rowan   +10 more
openalex   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]

Scientific Reports, 2016
AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
G. Antunes, A. C. Roque, F. M. Simoes-de-Souza   +2 more
openaire   +2 more sources

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Vitamin D Alterations in Food Regimens and Synaptic Transmission in Neuronal Circuit

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012
<p><strong><em>Background and Objectives:</em></strong> In nervous system, through specific channels and some ionotropic receptors, calcium ion involves in synaptic transmission vitamin D takes an important role in cellular ...
S Davari, M Salami, AR Talaei Zavareh, M Taghizadeh, A Jazayeri   +4 more
doaj   +2 more sources

Correction to: GPR68 deletion impairs hippocampal long-term potentiation and passive avoidance behavior [PDF]

, 2021
Yuanyuan Xu, Mike T. Lin, Xiang‐ming Zha   +2 more
openalex   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source

Stress and Corticosteroids Modulate Muscarinic Long Term Potentiation (mLTP) in the Hippocampus

Frontiers in Cellular Neuroscience, 2017
Stress influences synaptic plasticity, learning and memory in a steroid hormone receptor dependent manner. Based on these findings it has been proposed that stress could be a major risk factor for the development of cognitive decline and dementia ...
Efrat Shavit Stein, Ze’Ev Itsekson Hayosh, Andreas Vlachos, Nicola Maggio, Nicola Maggio, Nicola Maggio, Nicola Maggio   +6 more
doaj   +1 more source

All‐in‐One Analog AI Hardware: On‐Chip Training and Inference with Conductive‐Metal‐Oxide/HfOx ReRAM Devices

Advanced Functional Materials, EarlyView.
An all‐in‐one analog AI accelerator is presented, enabling on‐chip training, weight retention, and long‐term inference acceleration. It leverages a BEOL‐integrated CMO/HfOx ReRAM array with low‐voltage operation (<1.5 V), multi‐bit capability over 32 states, low programming noise (10 nS), and near‐ideal weight transfer.
Donato Francesco Falcone, Victoria Clerico, Wooseok Choi, Tommaso Stecconi, Folkert Horst, Laura Bégon‐Lours, Matteo Galetta, Antonio La Porta, Nikhil Garg, Fabien Alibart, Bert Jan Offrein, Valeria Bragaglia   +11 more
wiley   +1 more source

Symmetry Enhanced Unconventional Spin Current Anisotropy in a Collinear Antiferromagnet

Advanced Functional Materials, EarlyView.
Spin‐orbit torques (SOTs) are investigated in epitaxial FeSn, a topological antiferromagnet with kagome lattice symmetry. Combining experimental and theoretical approaches, the study identifies a six‐fold conventional damping‐like spin‐orbit torque (DL SOT), along with the coexistence of both six‐fold and uniaxial unconventional field‐like torque (FL ...
Pankhuri Gupta, Kacho Imtiyaz Ali Khan, Akash Kumar, Pratik Sahu, Rekha Agarwal, Artem Litvinenko, Nidhi Kandwal, Ram Singh Yadav, Birabar Ranjit Kumar Nanda, Johan Åkerman, Pranaba Kishor Muduli   +10 more
wiley   +1 more source