Results 51 to 60 of about 912,479 (304)

Long-Term Performance of High Strength Concrete [PDF]

open access: yesJournal of the Korea Concrete Institute, 2004
This paper describes an experimental investigation of how time-dependent deformations of high strength concretes are affected by maximum size of coarse aggregate, curing time, and relatively low sustained stress level. A set of high strength concrete mixes, mainly containing two different maximum sizes of coarse aggregate, have been used to investigate
Yeol Choi, Moon-Myung Kang
openaire   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

EMPIRICAL STRENGTH CRITERION OF COMPOSITE MATERIALS

open access: yesВестник Донского государственного технического университета, 2018
Empirical long-term strength criterion in terms of limit stress for constructive polymer materials considering ageing factor is found. The criterion corresponds to the type of Goldenblat - Kopnov.
O.G. OSYAEV
doaj  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Peripubertal aromatase inhibition in male rats has adverse long-term effects on bone strength and growth and induces prostatic hyperplasia

open access: yes, 2010
*This article is free to read on the publisher's website*\ud \ud Aromatase inhibitors have been increasingly used in boys with growth retardation to prolong the duration of growth and increase final height.
George A Werther   +15 more
core   +1 more source

CRITERIAL METHOD OF CALCULATIONS OF LONG-TERM STABILITY OF THE BOREHOLE

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2018
The article examines the possibility of applying the Mohr - Coulomb short-term strength criterion to the calculations of long-term stability of open oil wells. The results of calculation of long-term and short-term strength on the basis of the polygon of
O. A. Shipilova, S. V. Shafieva
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Effects of short-term, medium-term and long-term resistance exercise training on cardiometabolic health outcomes in adults: systematic review with meta-analysis [PDF]

open access: yes, 2018
Objective: To examine the effects of short-, medium- and long-term resistance exercise training (RET) on measures of cardio-metabolic health in adults. Design: Intervention systematic review Data sources: MEDLINE and Cochrane Library databases were
Aning, Jonathan   +11 more
core   +1 more source

Models for Predicting the Long-Term Strength of Rheonomic Materials

open access: yesApplied Sciences
Reliable modeling and prediction of the long-term strength of materials are relevant, as they allow for accurate determination of the service life of structures and components made from these materials.
Alibay Iskakbayev   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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