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Microbiome and their metabolites are increasingly being recognized for their role in colorectal cancer (CRC) carcinogenesis. Towards revealing new CRC biomarkers, we compared 16S rRNA gene sequencing and liquid chromatography-mass spectrometry (LC–MS ...
Jiahui Feng+12 more
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Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium
The rapid and high throughput discovery of long non coding RNAs (lncRNAs) has far outstripped the functional annotation of these novel transcripts in their respective cellular contexts.
Samatha Mathew+3 more
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Research progress on subcellular localization and function of long non-coding RNA [PDF]
The subcellular localization of long non-coding RNA(lncRNA) is closely related to its function. When localized in the nucleus, lncRNA can maintain chromatin structure, regulate gene transcription and participate in variable splicing of mRNA.
SU Yue, LIANG Linhui, HE Xianghuo
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Background Distant metastasis is the major cause of clear cell renal cell carcinoma (ccRCC)-associated mortality. However, molecular mechanisms involved in ccRCC metastasis remain to be fully understood.
Yanliang Wang+15 more
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Characterization of cervical canal and vaginal bacteria in pregnant women with cervical incompetence
Vaginal and cervical canal bacteria are associated with women’s health and pregnancy outcomes. Here, we compared their composition and characteristics in 37 reproductive-aged Chinese women including 24 pregnant women with cervical incompetence (vaginal ...
Meiguo Sun+8 more
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Interaction among long non‐coding RNA, micro‐RNA and mRNA in glioma
With the rapid development and wide application of gene sequencing, biotechnology, and informatics about cancer, it has been found that the main causes of malignant gliomas occurrence not only consist of abnormal mutations of protein‐coding genes but ...
Yang Chai, Shun Liu, Ming‐Xiang Xie
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Biological Function of Long Non-coding RNA (LncRNA) Xist
Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as
Wenlun Wang+7 more
semanticscholar +1 more source
N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC.
X. Yang+9 more
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Long non-coding RNAs (lncRNAs) are an increasingly studied group of non-protein coding transcripts with a wide variety of molecular functions gaining attention for their roles in numerous biological processes. Nearly 6,000 lncRNAs have been identified in
Marianne C. Kramer+13 more
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The Role of Non-Coding RNAs in Glioma
For decades, research in cancer biology has been focused on the protein-coding fraction of the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has become known that these entities not only function in numerous fundamental life ...
Anshika Goenka+6 more
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