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Microbiome and metabolic features of tissues and feces reveal diagnostic biomarkers for colorectal cancer

open access: yesFrontiers in Microbiology, 2023
Microbiome and their metabolites are increasingly being recognized for their role in colorectal cancer (CRC) carcinogenesis. Towards revealing new CRC biomarkers, we compared 16S rRNA gene sequencing and liquid chromatography-mass spectrometry (LC–MS ...
Jiahui Feng   +12 more
doaj   +1 more source

Long Non Coding RNA Based Regulation of Cerebrovascular Endothelium

open access: yesFrontiers in Genetics, 2022
The rapid and high throughput discovery of long non coding RNAs (lncRNAs) has far outstripped the functional annotation of these novel transcripts in their respective cellular contexts.
Samatha Mathew   +3 more
doaj   +1 more source

Research progress on subcellular localization and function of long non-coding RNA [PDF]

open access: yesJichu yixue yu linchuang, 2023
The subcellular localization of long non-coding RNA(lncRNA) is closely related to its function. When localized in the nucleus, lncRNA can maintain chromatin structure, regulate gene transcription and participate in variable splicing of mRNA.
SU Yue, LIANG Linhui, HE Xianghuo
doaj   +1 more source

LncRNA MILIP links YBX1 to translational activation of Snai1 and promotes metastasis in clear cell renal cell carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Distant metastasis is the major cause of clear cell renal cell carcinoma (ccRCC)-associated mortality. However, molecular mechanisms involved in ccRCC metastasis remain to be fully understood.
Yanliang Wang   +15 more
doaj   +1 more source

Characterization of cervical canal and vaginal bacteria in pregnant women with cervical incompetence

open access: yesFrontiers in Microbiology, 2022
Vaginal and cervical canal bacteria are associated with women’s health and pregnancy outcomes. Here, we compared their composition and characteristics in 37 reproductive-aged Chinese women including 24 pregnant women with cervical incompetence (vaginal ...
Meiguo Sun   +8 more
doaj   +1 more source

Interaction among long non‐coding RNA, micro‐RNA and mRNA in glioma

open access: yesIbrain, 2021
With the rapid development and wide application of gene sequencing, biotechnology, and informatics about cancer, it has been found that the main causes of malignant gliomas occurrence not only consist of abnormal mutations of protein‐coding genes but ...
Yang Chai, Shun Liu, Ming‐Xiang Xie
doaj   +1 more source

Biological Function of Long Non-coding RNA (LncRNA) Xist

open access: yesFrontiers in Cell and Developmental Biology, 2021
Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as
Wenlun Wang   +7 more
semanticscholar   +1 more source

METTL14 suppresses proliferation and metastasis of colorectal cancer by down-regulating oncogenic long non-coding RNA XIST

open access: yesMolecular Cancer, 2020
N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC.
X. Yang   +9 more
semanticscholar   +1 more source

A Conserved Long Intergenic Non-coding RNA Containing snoRNA Sequences, lncCOBRA1, Affects Arabidopsis Germination and Development

open access: yesFrontiers in Plant Science, 2022
Long non-coding RNAs (lncRNAs) are an increasingly studied group of non-protein coding transcripts with a wide variety of molecular functions gaining attention for their roles in numerous biological processes. Nearly 6,000 lncRNAs have been identified in
Marianne C. Kramer   +13 more
doaj   +1 more source

The Role of Non-Coding RNAs in Glioma

open access: yesBiomedicines, 2022
For decades, research in cancer biology has been focused on the protein-coding fraction of the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has become known that these entities not only function in numerous fundamental life ...
Anshika Goenka   +6 more
doaj   +1 more source

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