Results 11 to 20 of about 728,039 (351)
Biological Function of Long Non-coding RNA (LncRNA) Xist
Frontiers in Cell and Developmental Biology, 2021 Long non-coding RNAs (lncRNAs) regulate gene expression in a variety of ways at epigenetic, chromatin remodeling, transcriptional, and translational levels. Accumulating evidence suggests that lncRNA X-inactive specific transcript (lncRNA Xist) serves as
Wenlun Wang +7 more
semanticscholar +1 more source
Molecular Cancer, 2020 N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC.
X. Yang +9 more
semanticscholar +1 more source
MALAT1 Long Non-Coding RNA: Functional Implications
Non-Coding RNA, 2020 The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
G. Arun, Disha Aggarwal, D. Spector
semanticscholar +1 more source
Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders
Non-Coding RNA, 2021 Development is a complex process regulated both by genetic and epigenetic and environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression in several tissues including the brain.
V. Aliperti, J. Skonieczna, A. Cerase
semanticscholar +1 more source
PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs.
Deshpande, Sumukh +4 more
core +4 more sources
The functional role of long non-coding RNA in human carcinomas
Molecular Cancer, 2011 Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however
E. Gibb, Carolyn J. Brown, W. Lam
semanticscholar +1 more source
Long non-coding RNA-polycomb intimate rendezvous [PDF]
Open Biology, 2020 The interaction between polycomb-repressive complexes 1/2 (PRC1/2) and long non-coding RNA (lncRNA), such as the X inactive specific transcript Xist and the HOX transcript antisense RNA (HOTAIR), has been the subject of intense debate.
Andrea Cerase, Gian Gaetano Tartaglia
doaj +1 more source
Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]
, 2019 Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh +7 more
core +3 more sources
FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome
Nucleic Acids Research, 2017 Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the different classes of RNAs among the plethora of reconstructed transcripts ...
Valentin Wucher +21 more
semanticscholar +1 more source
Archives of Medical Science, 2019 Introduction This study was performed to explore the function of B-Raf proto-oncogene-activated non-coding RNA (BANCR) in laryngeal squamous cell carcinoma (LSCC) and cisplatin resistance.
Weiwei Han +4 more
doaj +1 more source