Results 11 to 20 of about 457,250 (297)
MALAT1 Long Non-Coding RNA: Functional Implications
Non-Coding RNA, 2020 The mammalian genome is pervasively transcribed and the functional significance of many long non-coding RNA (lncRNA) transcripts are gradually being elucidated.
G. Arun, Disha Aggarwal, D. Spector
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The functional role of long non-coding RNA in human carcinomas
Molecular Cancer, 2011 Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however
E. Gibb, Carolyn J. Brown, W. Lam
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FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome
Nucleic Acids Research, 2017 Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the different classes of RNAs among the plethora of reconstructed transcripts ...
Valentin Wucher +21 more
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Archives of Medical Science, 2019 Introduction This study was performed to explore the function of B-Raf proto-oncogene-activated non-coding RNA (BANCR) in laryngeal squamous cell carcinoma (LSCC) and cisplatin resistance.
Weiwei Han +4 more
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Expression of long non-coding RNA and mRNA in the hippocampus of mice with type 2 diabetes
Molecular Medicine Reports, 2018 Long non-coding RNAs (lncRNAs) serve key roles in cell growth, development and various diseases associated with the central nervous system. However, differential expression profiles of lncRNAs in type 2 diabetes have not been reported.
L. Ci +7 more
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Long non-coding RNA-polycomb intimate rendezvous [PDF]
Open Biology, 2020 The interaction between polycomb-repressive complexes 1/2 (PRC1/2) and long non-coding RNA (lncRNA), such as the X inactive specific transcript Xist and the HOX transcript antisense RNA (HOTAIR), has been the subject of intense debate.
Andrea Cerase, Gian Gaetano Tartaglia
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Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling
EMBO Molecular Medicine, 2016 The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao +15 more
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Translational Oncology, 2023 Objectives: To investigate the clinical significance of Chloride Intracellular Channel 1 (CLIC1) expression in esophageal squamous cell carcinoma (ESCC) and its functional contribution and molecular mechanisms to the progression of ESCC.
Huiwu Geng +12 more
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Long Non-Coding RNA in the Pathogenesis of Cancers
Cells, 2019 The incidence and mortality rate of cancer has been quickly increasing in the past decades. At present, cancer has become the leading cause of death worldwide. Most of the cancers cannot be effectively diagnosed at the early stage.
Yujing Chi +4 more
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Nucleic Acids Res., 2020 NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals.
Lianhe Zhao +15 more
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