Results 11 to 20 of about 588,548 (249)
Identification and function of long non-coding RNA [PDF]
Frontiers in Cellular Neuroscience, 2013 Long non-coding (lnc) RNAs are defined as non-protein coding RNAs distinct from housekeeping RNAs such as tRNAs, rRNAs, and snRNAs, and independent from small RNAs with specific molecular processing machinery such as micro- or piwi-RNAs.
Carl Ernst, Cynthia C. Morton
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Long non-coding RNAs in cancer [PDF]
Science China Life Sciences, 2012 Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, the Third Xiangya Hospital, Central South University, Changsha 410013, China; Key Laboratory of Carcinogenesis of Ministry of Health, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Cancer Research Institute, Central South ...
Zhaojian Gong +15 more
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On the classification of long non-coding RNAs [PDF]
RNA Biology, 2013 Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide variety of important biological processes. To make easier interpretation of lncRNA functionality and conduct deep mining on these transcribed sequences, it is convenient to classify lncRNAs into different groups.
Lina Ma, Vladimir B. Bajić, Zhang Zhang
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Long Non-Coding RNAs in Insects [PDF]
Animals, 2021 Only a small subset of all the transcribed RNAs are used as a template for protein translation, whereas RNA molecules that are not translated play a very important role as regulatory non-coding RNAs (ncRNAs). Besides traditionally known RNAs (ribosomal and transfer RNAs), ncRNAs also include small non-coding RNAs (sncRNAs) and long non-coding RNAs ...
Chhavi Choudhary +9 more
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Long Non-Coding RNA Epigenetics [PDF]
International Journal of Molecular Sciences, 2021 Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in ensuring cell functions and proper organism development by interacting with cellular compounds such as miRNA, mRNA, DNA and proteins. However, there is an additional level of lncRNA regulation, called lncRNA epigenetics, in gene expression control.
Marek Kazimierczyk, Jan Wrzesinski
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Long non-coding RNAs in oncourology
Non-coding RNA Research, 2021 For several decades, research in tumor biology has focused on the involvement of genes encoding a protein. Only recently has it been discovered that a whole class of molecules called non-coding RNAs (ncRNAs) play a key regulatory role in health and disease. Long noncoding RNAs (lncRNAs) are a group of noncoding RNAs longer than 200 nucleotides.
Ilgiz Gareev +10 more
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Long Non-Coding RNA in Cancer [PDF]
International Journal of Molecular Sciences, 2013 Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are emerging as new players in tumorigenesis due to their various functions in transcriptional, posttranscriptional and epigenetic mechanisms of gene regulation. LncRNAs are deregulated in a number of cancers, demonstrating both oncogenic and tumor suppressive roles, thus ...
Nina Hauptman, Damjan Glavač
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Long non‐coding RNA modifies chromatin [PDF]
BioEssays, 2011 AbstractCommon themes are emerging in the molecular mechanisms of long non‐coding RNA‐mediated gene repression. Long non‐coding RNAs (lncRNAs) participate in targeted gene silencing through chromatin remodelling, nuclear reorganisation, formation of a silencing domain and precise control over the entry of genes into silent compartments.
Alka Saxena, Piero Carninci??
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The Involvement of Long Non-Coding RNAs in Bone [PDF]
International Journal of Molecular Sciences, 2021 A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone formation and resorption, pathological conditions affecting the bone may arise. In recent years, emerging evidence has shown that epigenetic mechanisms play an important role during osteoblastogenesis and osteoclastogenesis processes, including long non-coding RNAs (
Aurilia C. +5 more
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PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs.
Deshpande, Sumukh +4 more
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