Results 281 to 290 of about 718,965 (394)

Functions and mechanisms of long non-coding RNA in esophageal squamous cell carcinoma (Review). [PDF]

Oncol Lett
Lin Y, Lv Z, Xie H, Zhao W, Pu R, Zhang Z, Jin H.   +6 more
europepmc   +1 more source

Nrf2 Drives Epigenetic Reprogramming and Acts as the Master Regulator of KLF4 Expression and Activity in Arsenic‐Induced Transformation

Advanced Science, EarlyView.
Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang, Zhuoyue Bi, Jessica Bamrah, Yiran Qiu, Wenxuan Zhang, Bandar Saeed Almutairy, Haoyan Ji, John D. Haley, Chitra Thakur, Fei Chen   +9 more
wiley   +1 more source

Long non-coding RNA TMEM51-AS1 inhibits colorectal cancer progression. [PDF]

Discov Oncol
Wu D, Xia Q, Su X, Mao Y, Mao J, Ding Q, Liu J, Zhong W, Zhang X, Li H, Duan S.   +10 more
europepmc   +1 more source

Long Non-Coding RNA Expression Profiling of Mouse Testis during Postnatal Development

, 2013
Jin Sun, Yi Lin, Ji Wu
openalex   +2 more sources

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Long non-coding RNA in the regulation of cell death in hepatocellular carcinoma. [PDF]

World J Clin Oncol
Wang J, Liu ZX, Huang ZH, Wen J, Rao ZZ.
europepmc   +1 more source

Comprehensive Analysis of Long Non-Coding RNAs in Ovarian Cancer Reveals Global Patterns and Targeted DNA Amplification

, 2013
Rozita Akrami, Anders J. Skanderup, Jessica I. Hoell, Nikolaus Schultz, Chris Sander, Erik Larsson   +5 more
openalex   +2 more sources

Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells [PDF]

, 2014
Chengwu Zeng, Yan Xu, Ling Xu, Xibao Yu, Jingjing Cheng, Lijian Yang, Shaohua Chen, Yangqiu Li   +7 more
openalex   +1 more source

Integrative Omics Reveals Glutamine Catabolism‐Driven Apoptotic Suppression in Monocytes upon Mechanical Unloading

Advanced Science, EarlyView.
This research integrated multi‐omics analysis of bone tissue from HLU and control mice revealed that mechanical unloading suppresses intrinsic apoptosis and augments glutamine (Gln) catabolism in osteoclast lineage cells. The findings highlight pivotal roles for SLC1A5‐mediated Gln metabolism and XIAP/Diablo axis‐mediated apoptosis suppression.
Yi Ding, Fan Tong, Mingqiu Liu, Pin Yang, Jing Zeng, Yinghua Wei, Chunlin Li, Dong Li, Cheng Chang, Yangjun Zhang, Shaoqiong Yi, Fan Hu, Wenjie Shu, Lingqiang Zhang, Chun‐Ping Cui   +14 more
wiley   +1 more source

The dysregulation and regulatory mechanism of long non-coding RNA LBX2-AS1 in children with epilepsy. [PDF]

Ital J Pediatr
Li Q, Li N.
europepmc   +1 more source