Results 281 to 290 of about 703,919 (374)

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Cell-type specific effects of the long non-coding RNA HIF1A-AS3 on HIF1A expression in kidney cells. [PDF]

Sci Rep
Reichelt-Wurm S, Knauss L, Strasser B, Scharf M, Holler K, Eggenhofer E, Kretz M, Banas B, Banas MC.   +8 more
europepmc   +1 more source

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer [PDF]

, 2014
Ehsan Malek, Sajjeev Jagannathan, James J. Driscoll   +2 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

A long non-coding RNA <i>lncRNA18313</i> regulates resistance against cadmium stress in wheat. [PDF]

Front Plant Sci
Zhao S, Bai H, Fan Z, Zhu M, Qiu Z.
europepmc   +1 more source

Getting to the heart of the matter: long non-coding RNAs in cardiac development and disease

, 2013
Johanna C. Scheuermann, Laurie A. Boyer
openalex   +2 more sources

Uncovering RNA Editing Sites in Long Non-Coding RNAs [PDF]

, 2014
Ernesto Picardi, Anna Maria Dâ€TMErchia, Angela Gallo, Antonio Montalvo, Graziano Pesole   +4 more
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Long non-coding RNA SNHG7 as a key driver of colorectal cancer proliferation and metastasis by inhibiting cuproptosis. [PDF]

Eur J Med Res
Guo X, He X, Chen W, Zhou J, Lyu Z, Li Z, Li Y.   +6 more
europepmc   +1 more source

Long non-coding RNAs learn the importance of being in vivo [PDF]

, 2014
Jhumku D. Kohtz
openalex   +1 more source