Results 21 to 30 of about 728,039 (351)

Expression of long non-coding RNA and mRNA in the hippocampus of mice with type 2 diabetes

Molecular Medicine Reports, 2018
Long non-coding RNAs (lncRNAs) serve key roles in cell growth, development and various diseases associated with the central nervous system. However, differential expression profiles of lncRNAs in type 2 diabetes have not been reported.
L. Ci, De-Shan Liu, Jing Yang, Y. Liu, Chang-Ling Li, Xi Zhang, Chun Mei Ma, Rui-ting Hu   +7 more
semanticscholar   +1 more source

Long non-coding RNAs era in liver cancer [PDF]

, 2015
Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core   +1 more source

Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

EMBO Molecular Medicine, 2016
The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao, Xiao‐Qun Wang, Yu‐Jie Li, Kun Shan, Hong Yang, Yang‐Ning‐Zhi Wang, Mu‐Di Yao, Chang Liu, Xiu‐Miao Li, Yi Shen, Jing‐Yu Liu, Hong Cheng, Jun Yuan, Yang‐Yang Zhang, Qin Jiang, Biao Yan   +15 more
doaj   +2 more sources

Apparent non-canonical trans-splicing is generated by reverse transcriptase in vitro [PDF]

, 2010
Trans-splicing, the in vivo joining of two RNA molecules, is well characterized in several groups of simple organisms but was long thought absent from fungi, plants and mammals.
David Tollervey, DS Rickman, E Gilboa, ES Svarovskaia, F Perocchi, GX Luo, H Li, HM Temin, J Cocquet, J Houseley, J Sambrook, Jonathan Houseley, KEM Hastings, M Geiszt, M Ouhammouch, P Kapranov, P Unneberg, RH Herai, RM Mader, S Zhu, SW Roy, T Horiuchi, Thomas Preiss, TR Gingeras, X Li, X Niu, XC Zeng   +26 more
core   +9 more sources

NONCODEV6: an updated database dedicated to long non-coding RNA annotation in both animals and plants

Nucleic Acids Res., 2020
NONCODE (http://www.noncode.org/) is a comprehensive database of collection and annotation of noncoding RNAs, especially long non-coding RNAs (lncRNAs) in animals.
Lianhe Zhao, Jiajia Wang, Yanyan Li, Tingrui Song, Yang Wu, Shuangsang Fang, Dechao Bu, Hui Li, Liang Sun, D. Pei, Yu Zheng, Jianqin Huang, Mingqing Xu, Runsheng Chen, Yi Zhao, Shunmin He   +15 more
semanticscholar   +1 more source

Long non-coding RNA deregulation in tongue squamous cell carcinoma [PDF]

, 2014
Background. The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). Methods.
Chan, JYW, Gao, W, Wong, TS
core   +8 more sources

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Long Non-Coding RNA in the Pathogenesis of Cancers

Cells, 2019
The incidence and mortality rate of cancer has been quickly increasing in the past decades. At present, cancer has become the leading cause of death worldwide. Most of the cancers cannot be effectively diagnosed at the early stage.
Yujing Chi, Di Wang, Junpei Wang, Weidong Yu, Jichun Yang   +4 more
semanticscholar   +1 more source

A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression [PDF]

, 2015
Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are ...
AC Thénié, B Holmqvist, B Kuzin, B Moreno-Lopez, BL Sopher, C-H Cheng, D Dahary, DS Bredt, E Ciani, E Pavesi, GB Robb, J Chen, J Garthwaite, J-T Li, JB Kelley, JE Fish, JH Brann, K Matsui, KY Kwan, L Zhou, MA Faghihi, MA Packer, ME Evangelopoulos, ME Evangelopoulos, MHT Ling, N Peunova, P Ogilvie, RG Tremblay, S Hindley, S Korneev, SA Korneev, SA Korneev, SA Korneev, SA Korneev, SM Gibbs, SR Vincent, U Forstermann, V Calabrese, Y Zhang   +38 more
core   +1 more source

Long non-coding RNA and diseases [PDF]

Jichu yixue yu linchuang
Long non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.

doaj   +1 more source