Results 21 to 30 of about 588,548 (249)
Long Non-Coding RNAs in the Cytoplasm
Genomics, Proteomics & Bioinformatics, 2016 Abstract An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic genome are important regulators in different aspects of cellular events. Cytoplasm is the residence and the site of action for many lncRNAs. The cytoplasmic lncRNAs play indispensable roles with multiple molecular mechanisms in animal and human ...
Farooq Rashid, Abdullah Shah, Ge Shan
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Long non-coding RNAs and enhancers [PDF]
Current Opinion in Genetics & Development, 2011 Long non-coding RNAs (ncRNAs) are emerging as important regulatory factors in mammalian genomics. A number of reports within the last 2 years have identified thousands of actively expressed long ncRNA transcripts with distinct properties. The long ncRNAs show differential expression patterns and regulation in a wide variety of cells and tissues, adding
Ulf Andersson Ørom, Ramin Shiekhattar
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The non-coding landscape of head and neck squamous cell carcinoma. [PDF]
, 2016 Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease marked by frequent recurrence and metastasis and stagnant survival rates. To enhance molecular knowledge of HNSCC and define a non-coding RNA (ncRNA) landscape of the disease, we ...
Grandis, Jennifer R +17 more
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Long non‐coding RNAs in melanoma [PDF]
Cell Proliferation, 2018 AbstractMelanoma is the most lethal cutaneous cancer with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have shed new insights into the mechanism of melanoma development, the involvement of regulatory non‐coding RNAs remain unclear.
Xin Yu +4 more
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PVT1: a rising star among oncogenic long non-coding RNAs [PDF]
, 2015 It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and (mis)function.
Colombo, Teresa +3 more
core +8 more sources
Long non-coding RNAs in neurodevelopmental disorders [PDF]
Frontiers in Molecular Neuroscience, 2013 Recent studies have emphasized an important role for long non-coding RNAs (lncRNA) in epigenetic regulation, development, and disease. Despite growing interest in lncRNAs, the mechanisms by which lncRNAs control cellular processes are still elusive. Improved understanding of these mechanisms is critical, because the majority of the mammalian genome is ...
Ilse Ida Gerarda Maria Van De Vondervoort +15 more
openaire +6 more sources
Long non-coding RNAs era in liver cancer [PDF]
, 2015 Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core +1 more source
Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling
EMBO Molecular Medicine, 2016 The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao +15 more
doaj +2 more sources
Viral RNAs are unusually compact. [PDF]
, 2014 A majority of viruses are composed of long single-stranded genomic RNA molecules encapsulated by protein shells with diameters of just a few tens of nanometers.
Ben-Shaul, Avinoam +6 more
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Translational Oncology, 2023 Objectives: To investigate the clinical significance of Chloride Intracellular Channel 1 (CLIC1) expression in esophageal squamous cell carcinoma (ESCC) and its functional contribution and molecular mechanisms to the progression of ESCC.
Huiwu Geng +12 more
doaj