Results 21 to 30 of about 739,569 (400)
Molecular Cancer, 2020 N6-methyladenosine (m6A) is the most prevalent RNA epigenetic regulation in eukaryotic cells. However, understanding of m6A in colorectal cancer (CRC) is very limited. We designed this study to investigate the role of m6A in CRC.
X. Yang +9 more
semanticscholar +1 more source
The functional role of long non-coding RNA in human carcinomas
Molecular Cancer, 2011 Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however
E. Gibb, Carolyn J. Brown, W. Lam
semanticscholar +1 more source
The Role of Non-Coding RNAs in Glioma
Biomedicines, 2022 For decades, research in cancer biology has been focused on the protein-coding fraction of the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has become known that these entities not only function in numerous fundamental life ...
Anshika Goenka +6 more
doaj +1 more source
Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]
, 2019 Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh +7 more
core +3 more sources
FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome
Nucleic Acids Research, 2017 Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify the different classes of RNAs among the plethora of reconstructed transcripts ...
Valentin Wucher +21 more
semanticscholar +1 more source
Long non-coding RNAs and enhancers [PDF]
Current Opinion in Genetics & Development, 2011 Long non-coding RNAs (ncRNAs) are emerging as important regulatory factors in mammalian genomics. A number of reports within the last 2 years have identified thousands of actively expressed long ncRNA transcripts with distinct properties. The long ncRNAs show differential expression patterns and regulation in a wide variety of cells and tissues, adding
Ulf Andersson, Ørom, Ramin, Shiekhattar
openaire +2 more sources
Apparent non-canonical trans-splicing is generated by reverse transcriptase in vitro [PDF]
, 2010 Trans-splicing, the in vivo joining of two RNA molecules, is well characterized in several groups of simple organisms but was long thought absent from fungi, plants and mammals.
David Tollervey +26 more
core +9 more sources
Archives of Medical Science, 2019 Introduction This study was performed to explore the function of B-Raf proto-oncogene-activated non-coding RNA (BANCR) in laryngeal squamous cell carcinoma (LSCC) and cisplatin resistance.
Weiwei Han +4 more
doaj +1 more source
Long non-coding RNAs era in liver cancer [PDF]
, 2015 Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core +1 more source
Expression of long non-coding RNA and mRNA in the hippocampus of mice with type 2 diabetes
Molecular Medicine Reports, 2018 Long non-coding RNAs (lncRNAs) serve key roles in cell growth, development and various diseases associated with the central nervous system. However, differential expression profiles of lncRNAs in type 2 diabetes have not been reported.
L. Ci +7 more
semanticscholar +1 more source