Results 21 to 30 of about 605,748 (301)

Downregulation of long non-coding RNA B-Raf proto-oncogene-activated non-coding RNA reverses cisplatin resistance in laryngeal squamous cell carcinoma

Archives of Medical Science, 2019
Introduction This study was performed to explore the function of B-Raf proto-oncogene-activated non-coding RNA (BANCR) in laryngeal squamous cell carcinoma (LSCC) and cisplatin resistance.
Weiwei Han, Lin Niu, Lin Wang, Jixiang Liu, Huanying Li   +4 more
doaj   +1 more source

Long non-coding RNAs era in liver cancer [PDF]

, 2015
Hepatocellular carcinoma (HCC) is one of the most common malignancies leading to high mortality rates in the general population and the sixth most common cancer worldwide.
Guerrieri, Francesca
core   +1 more source

MicroRNA-encoding long non-coding RNAs [PDF]

BMC Genomics, 2008
Abstract Background Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these ml-ncRNAs are beginning to be unravelled, no functional information is available for the large majority of these transcripts.
Zhu Xiaopeng, He Dandan, He Housheng, Skogerbø Geir, Liu Changning, Su Hua, He Shunmin, Liu Tao, Zhao Yi, Chen Runsheng   +9 more
openaire   +3 more sources

Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling

EMBO Molecular Medicine, 2016
The nervous and vascular systems, although functionally different, share many common regulators of function maintenance. Long non‐coding RNAs (lncRNAs) are important players in many biological processes and human disorders.
Jin Yao, Xiao‐Qun Wang, Yu‐Jie Li, Kun Shan, Hong Yang, Yang‐Ning‐Zhi Wang, Mu‐Di Yao, Chang Liu, Xiu‐Miao Li, Yi Shen, Jing‐Yu Liu, Hong Cheng, Jun Yuan, Yang‐Yang Zhang, Qin Jiang, Biao Yan   +15 more
doaj   +2 more sources

Long non-coding RNA deregulation in tongue squamous cell carcinoma [PDF]

, 2014
Background. The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). Methods.
Chan, JYW, Gao, W, Wong, TS
core   +8 more sources

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Long non‐coding RNAs in melanoma [PDF]

Cell Proliferation, 2018
AbstractMelanoma is the most lethal cutaneous cancer with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have shed new insights into the mechanism of melanoma development, the involvement of regulatory non‐coding RNAs remain unclear.
Xin Yu, Heyi Zheng, Gary Tse, Matthew TV Chan, William KK Wu   +4 more
openaire   +2 more sources

A novel long non-coding natural antisense RNA is a negative regulator of Nos1 gene expression [PDF]

, 2015
Long non-coding natural antisense transcripts (NATs) are widespread in eukaryotic species. Although recent studies indicate that long NATs are engaged in the regulation of gene expression, the precise functional roles of the vast majority of them are ...
AC Thénié, B Holmqvist, B Kuzin, B Moreno-Lopez, BL Sopher, C-H Cheng, D Dahary, DS Bredt, E Ciani, E Pavesi, GB Robb, J Chen, J Garthwaite, J-T Li, JB Kelley, JE Fish, JH Brann, K Matsui, KY Kwan, L Zhou, MA Faghihi, MA Packer, ME Evangelopoulos, ME Evangelopoulos, MHT Ling, N Peunova, P Ogilvie, RG Tremblay, S Hindley, S Korneev, SA Korneev, SA Korneev, SA Korneev, SA Korneev, SM Gibbs, SR Vincent, U Forstermann, V Calabrese, Y Zhang   +38 more
core   +1 more source

Long non-coding RNA and diseases [PDF]

Jichu yixue yu linchuang
Long non-coding RNA (lncRNA) is a class of endogenous non-coding RNA with a length of more than 200 nt. Due to lack of open reading frame (ORF), they lack the ability to directly encode proteins, but they play a crucial role in gene regulation.

doaj   +1 more source

Identification and function of long non-coding RNA [PDF]

, 2013
Long non-coding (lnc) RNAs are defined as non-protein coding RNAs distinct from housekeeping RNAs such as tRNAs, rRNAs, and snRNAs, and independent from small RNAs with specific molecular processing machinery such as micro- or piwi-RNAs.
Ernst, Carl, Morton, Cynthia C.
core   +2 more sources