Results 41 to 50 of about 728,039 (351)
ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation
Cellular Physiology and Biochemistry, 2018 Background/Aims: Mounting evidence suggests that epitranscriptional modifications regulate multiple cellular processes. N6-Methyladenosine (m6A), the most abundant reversible methylation of mRNA, has critical roles in cancer pathogenesis.
Yuan He +10 more
semanticscholar +1 more source
Review: Long non-coding RNA in livestock
Animal, 2020 Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi +2 more
doaj +1 more source
Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are important regulators of gene expression that influence almost every step in the life cycle of genes, from transcription to mRNA splicing, RNA decay, and translation.
Ballarino, Monica +2 more
core +2 more sources
Molecular Cancer, 2019 The long non-coding RNA PVT1 (lncRNA PVT1) has been reported to act as an oncogenic regulator of several cancers. However, its expression and function in gallbladder cancer (GBC) remain largely unknown.
Jianan Chen +13 more
semanticscholar +1 more source
Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome [PDF]
, 2012 Brain aging frequently underlies cognitive decline and is a major risk factor for neurodegenerative conditions. The exact molecular mechanisms underlying brain aging, however, remain unknown. Whole transcriptome sequencing provides unparalleled depth and
Brian Merry +4 more
core +1 more source
An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes
Frontiers in Oncology, 2020 The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which are reported in many studies as being overexpressed in various cancers.
Alina-Andreea Zimta +5 more
semanticscholar +1 more source
Respiratory Research, 2020 Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao +5 more
doaj +1 more source
LncRNADisease: a database for long-non-coding RNA-associated diseases
Nucleic Acids Res., 2012 In this article, we describe a long-non-coding RNA (lncRNA) and disease association database (LncRNADisease), which is publicly accessible at http://cmbi.bjmu.edu.cn/lncrnadisease.
Geng Chen +8 more
semanticscholar +1 more source
Long non-coding RNA SOX2OT: Expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis [PDF]
, 2015 SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region.
Jazi, M.S. +3 more
core +1 more source
PLoS ONE, 2022 Colorectal cancer (CRC) ranks the third in cancers and the second in the reasons of cancer-related death. More evidence indicates that long non-coding RNA participates in tumor initiation and progression. It’s known that cancer susceptibility candidate 9
Heping Zhang +5 more
doaj +2 more sources