Results 51 to 60 of about 593,894 (334)
MicroRNA-encoding long non-coding RNAs [PDF]
BMC Genomics, 2008 Abstract Background Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these ml-ncRNAs are beginning to be unravelled, no functional information is available for the large majority of these transcripts.
Shunmin He +9 more
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PLoS ONE, 2022 Colorectal cancer (CRC) ranks the third in cancers and the second in the reasons of cancer-related death. More evidence indicates that long non-coding RNA participates in tumor initiation and progression. It’s known that cancer susceptibility candidate 9
Heping Zhang +5 more
doaj +2 more sources
Non-coding RNAs in Transcriptional Regulation [PDF]
, 2015 Transcriptional gene silencing guided by small RNAs is a process conserved from protozoa to mammals. Small RNAs loaded into Argonaute family proteins direct repressive histone modifications or DNA cytosine methylation to homologous regions of the genome.
Aravin, Alexei A., Chen, Yung-Chia Ariel
core +1 more source
Whole transcriptome profiling reveals the RNA content of motor axons [PDF]
, 2015 Most RNAs within polarized cells such as neurons are sorted subcellularly in a coordinated manner. Despite advances in the development of methods for profiling polyadenylated RNAs from small amounts of input RNA, techniques for profiling coding and non ...
Appenzeller, Silke +5 more
core +1 more source
The Role of Long Non-Coding RNAs in Osteosarcoma [PDF]
Non-Coding RNA, 2018 Long non-coding RNAs (lncRNAs) constitute non-protein coding transcripts with a size > than 200 nucleotides. They are involved in many cellular processes, such as chromatin remodelling, transcription, and gene expression. They play a role in the development, progression, and invasion of many human cancers, including osteosarcoma.
Maria Smolle, Martin Pichler
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Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Tumor Biology, 2017 Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood.
Fangyuan Jing +6 more
doaj +1 more source
Long non coding RNA H19: An emerging therapeutic target in fibrosing diseases
Autoimmunity, 2020 Fibrosis is characterised by excessive deposition of the extracellular matrix (ECM) and develops because of fibroblast differentiation during the process of inflammation. There are few effective treatment options for this diseases due to the aetiology of
Juan Li +4 more
doaj +1 more source
Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA [PDF]
, 2017 Precise regulation of Egr2 transcription is fundamentally important to the control of peripheral myelination. Here, we describe a long non-coding RNA antisense to the promoter of Egr2 (Egr2-AS-RNA).
Langer, Robert S +6 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Long Non-Coding RNAs in Vascular Inflammation [PDF]
Frontiers in Cardiovascular Medicine, 2018 Less than 2% of the genome encodes for proteins. Accumulating studies have revealed a diverse set of RNAs derived from the non-coding genome. Among them, long non-coding RNAs (lncRNAs) have garnered widespread attention over recent years as emerging regulators of diverse biological processes including in cardiovascular disease (CVD).
Haemmig, Stefan +2 more
openaire +5 more sources