Results 61 to 70 of about 718,965 (394)
Long Non-Coding RNAs in Endometrial Carcinoma [PDF]
International Journal of Molecular Sciences, 2015 Endometrial carcinoma (EC), the second most common form of gynaecological malignancy, can be divided into two distinct sub-types: Type I tumours arise from hyperplastic endometrium and typically effect women around the time of menopause, whereas type II tumours arise in postmenopausal women from atrophic endometrium.
Maria Smolle +4 more
openaire +4 more sources
Role of Non-Coding RNAs in Colorectal Cancer: Focus on Long Non-Coding RNAs
International Journal of Molecular Sciences, 2022 Colorectal cancer is one of the most common causes of cancer-related deaths worldwide. Despite the advances in the knowledge of pathogenetic molecular mechanisms and the implementation of more effective drug treatments in recent years, the overall survival rate of patients remains unsatisfactory.
Lulli, Matteo +4 more
openaire +3 more sources
ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation
Cellular Physiology and Biochemistry, 2018 Background/Aims: Mounting evidence suggests that epitranscriptional modifications regulate multiple cellular processes. N6-Methyladenosine (m6A), the most abundant reversible methylation of mRNA, has critical roles in cancer pathogenesis.
Yuan He +10 more
semanticscholar +1 more source
An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes
Frontiers in Oncology, 2020 The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which are reported in many studies as being overexpressed in various cancers.
Alina-Andreea Zimta +5 more
semanticscholar +1 more source
Review: Long non-coding RNA in livestock
Animal, 2020 Less than 2% of mammalian genomes code for proteins, but ‘the majority of its bases can be found in primary transcripts’ – a phenomenon termed the pervasive transcription, which was first reported in 2007.
B. Kosinska-Selbi +2 more
doaj +1 more source
LncRNADisease: a database for long-non-coding RNA-associated diseases
Nucleic Acids Res., 2012 In this article, we describe a long-non-coding RNA (lncRNA) and disease association database (LncRNADisease), which is publicly accessible at http://cmbi.bjmu.edu.cn/lncrnadisease.
Geng Chen +8 more
semanticscholar +1 more source
MicroRNA-encoding long non-coding RNAs [PDF]
BMC Genomics, 2008 Abstract Background Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these ml-ncRNAs are beginning to be unravelled, no functional information is available for the large majority of these transcripts.
Shunmin He +9 more
openaire +4 more sources
Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are important regulators of gene expression that influence almost every step in the life cycle of genes, from transcription to mRNA splicing, RNA decay, and translation.
Ballarino, Monica +2 more
core +2 more sources
Respiratory Research, 2020 Background Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases.
Yifang Liao +5 more
doaj +1 more source
Long non-coding RNA SOX2OT: Expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis [PDF]
, 2015 SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region.
Jazi, M.S. +3 more
core +1 more source