Results 201 to 210 of about 6,663,585 (252)

Correction: Long noncoding RNA TLNC1 promotes the growth and metastasis of liver cancer via inhibition of p53 signaling. [PDF]

Mol Cancer
Yuan K, Lan J, Xu L, Feng X, Liao H, Xie K, Wu H, Zeng Y.   +7 more
europepmc   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

The FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Alternative probe chemistries for single-molecule analysis of long noncoding RNA. [PDF]

J Biol Chem
Pai KR, Martin AM, Kadrmas M, Widom JR.
europepmc   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

Spheroids and organoids to study long noncoding RNAs in cancer: how they could replace animal models. [PDF]

Cancer Metastasis Rev
Capela AM, Pessoa J, Arede H, Bernardes de Jesus B.   +3 more
europepmc   +1 more source

Toward a minimal amino acid alphabet for protein design

The FEBS Journal, EarlyView.
Proteins are built from 20 canonical amino acids; however, it is interesting to investigate whether they can also be formed from reduced amino acid alphabets. Using protein design, we designed proteins based on all alphabets comprising 2 to 10 ‘early’ amino acids (those likely to have been present before the origin of life).
Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok, Karolína Loužecká, Vladimír Setnička, Petra Lipovová   +5 more
wiley   +1 more source

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

The FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson, Elham Nikbakht, Hayley O'Neill, Larisa Margaret Haupt, Paul Joseph Dunn   +4 more
wiley   +1 more source

Long noncoding RNA FOXP1-DT modulates regulatory T cells in Graves' disease. [PDF]

Sci Rep
Xu Q, Lu C, Xu J, Zhou M, Li S, Shen X, Wang S, Liu Y, Peng H.   +8 more
europepmc   +1 more source

Statement of Retraction: Long noncoding RNA MALAT1 knockdown inhibits progression of anaplastic thyroid carcinoma by regulating miR-200a-3p/FOXA1. [PDF]

Cancer Biol Ther
europepmc   +1 more source