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Long-Read Metagenomics and CAZyme Discovery
2023Microorganisms play a primary role in regulating biogeochemical cycles and are a valuable source of enzymes that have biotechnological applications, such as carbohydrate-active enzymes (CAZymes). However, the inability to culture the majority of microorganisms that exist in natural ecosystems restricts access to potentially novel bacteria and ...
Ferrillo, Alessandra +6 more
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Informatics for PacBio Long Reads
2019In this article, we review the development of a wide variety of bioinformatics software implementing state-of-the-art algorithms since the introduction of SMRT sequencing technology into the field. We focus on the three major categories of development: read mapping (aligning to reference genomes), de novo assembly, and detection of structural variants.
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Probably Correct: Rescuing Repeats with Short and Long Reads
Genes, 2021Monika Cechova, Cechova Monika
exaly
Assembly-free discovery of human novel sequences using long reads
DNA Research, 2022Ruibang Luo, Tak-Wah Lam, Lam Tak-Wah
exaly
The Cancer Genome in the Long Reads Era
Cancer genomics, driven by advancements in sequencing technologies, is rapidly transforming our understanding of tumor biology. The advent of high-throughput short-read sequencing technologies has enabled a paradigm shift in cancer genomics, providing unprecedented resolution of mutations that drive tumorigenesis.openaire +2 more sources
KFinger: Capturing Overlaps Between Long Reads by Using Lyndon Fingerprints
Lecture Notes in Computer Science, 2022Paola Bonizzoni +2 more
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I-CONVEX: Fast and Accurate de Novo Transcriptome Recovery from Long Reads
Communications in Computer and Information Science, 2023Elizabeth Tseng +2 more
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