Results 1 to 10 of about 647,684 (75)

Long-Term Potentiation and Memory [PDF]

open access: yesPhysiological Reviews, 2004
Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004; 10.1152/physrev.00014.2003.—One of the most significant challenges in neuroscience is to identify the cellular and molecular processes that underlie learning and memory formation. The past decade has seen remarkable progress in understanding changes that accompany certain forms
Lynch, M. A., Ma, Lynch
openaire   +3 more sources

Modified scattering for nonlinear Schrödinger equations with long-range potentials [PDF]

open access: yes, 2023
We study the final state problem for the nonlinear Schr\"{o}dinger equation with a critical long-range nonlinearity and a long-range linear potential. Given a prescribed asymptotic profile which is different from the free evolution, we construct a unique global solution scattering to the profile.
arxiv   +1 more source

Long-term potentiation in the Eocene [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract The first ten years of long-term potentiation (LTP) research are reviewed. Surprisingly, given the intensity of current interest, the discovery paper did not trigger a wave of follow-on experiments. Despite this, the initial work laid out what ultimately became standard questions and paradigms.
openaire   +3 more sources

Long-term potentiation and long-term depression: a clinical perspective [PDF]

open access: yesClinics, 2011
Long-term potentiation and long-term depression are enduring changes in synaptic strength, induced by specific patterns of synaptic activity, that have received much attention as cellular models of information storage in the central nervous system.
Bliss, Timothy V.P., Cooke, Sam F.
openaire   +6 more sources

The discovery of long-term potentiation [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract This paper describes circumstances around the discovery of long-term potentiation (LTP). In 1966, I had just begun independent work for the degree of Dr medicinae (PhD) in Per Andersen’s laboratory in Oslo after an eighteen-month apprenticeship with him.
openaire   +3 more sources

Long-range potential scattering: Converting long-range potential to short-range potential by tortoise coordinate [PDF]

open access: yesJ. Math. Phys. 62, 122102 (2021), 2018
Inspired by general relativity, we suggest an approach for long-range potential scattering. In scattering theory, there is a general theory for short-range potential scattering, but there is no general theory for long-range potential scattering. This is because the scattering boundary conditions for all short-range potentials are the same, but for ...
arxiv   +1 more source

Long-term potentiation and memory [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract The discovery of long-term potentiation (LTP) transformed research on the neurobiology of learning and memory. This did not happen overnight, but the discovery of an experimentally demonstrable phenomenon reflecting activity-driven neuronal and synaptic plasticity changed discussions about what might underlie learning from ...
openaire   +3 more sources

Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]

open access: yesScientific Reports, 2016
AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
Fábio M. Simões-de-Souza   +2 more
openaire   +3 more sources

A prelude to long-term potentiation [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2003
Abstract Searching for premonitory studies of hippocampal long-term potentiation (LTP), there is a paucity of data. While synaptic enhancement during repetitive activation was studied in several reports from many groups between 1955 and 1967, the reported after-effects were short, at the most lasting a few minutes.
openaire   +3 more sources

Short-Term Plasticity and Long-Term Potentiation in Magnetic Tunnel Junctions: Towards Volatile Synapses [PDF]

open access: yesPhys. Rev. Applied 5, 024012 (2016), 2015
Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic applications, recent studies in neuroscience have revealed that biological synapses undergo meta-stable volatile ...
arxiv   +1 more source

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