Results 271 to 280 of about 169,643 (326)

Reflecting on 50 years of long-term potentiation: Insights from the Royal Society's LTP50 conference. [PDF]

Brain Neurosci Adv
Mitchell-Heggs R, Tse D.
europepmc   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins. [PDF]

Philos Trans R Soc Lond B Biol Sci
Ondrejcak T, Klyubin I, Hu NW, Yang Y, Zhang Q, Rodriguez BJ, Rowan MJ.   +6 more
europepmc   +1 more source

The Expression of Neurodegeneration-Related Genes in the Hippocampus of Hypothyroid Rats Following Long-Term Potentiation. [PDF]

Eurasian J Med
Altunkaya M, Babur E, Barutçu Ö, Süer C, Dursun N.   +4 more
europepmc   +1 more source

Norepinephrine triggers glutamatergic long-term potentiation in hypothalamic paraventricular nucleus magnocellular neuroendocrine cells through postsynaptic β1-AR/PKA signaling pathway in vitro in rats. [PDF]

Korean J Physiol Pharmacol
Jin JR, Zhang ZY, Chu CP, Li YZ, Qiu DL.
europepmc   +1 more source

The Association of Hippocampal Long-Term Potentiation-Induced Gene Expression with Genetic Risk for Psychosis. [PDF]

Int J Mol Sci
Wellard NL, Clifton NE, Rees E, Thomas KL, Hall J.   +4 more
europepmc   +1 more source

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Long-Term Potentiation

Annual Review of Neuroscience, 1987
History and Definition In 1973, two reports appeared in the Journal of Physiology that described a long-term potentiation (L TP) of synaptic transmission at a monosynaptic junction in the mammalian eNS. These two papers, one dealing with the anesthetized rabbit preparation (Bliss & L0mo 1973) and the other dealing with the unanesthetized rabbit (Bliss &
T J, Teyler, P, DiScenna
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Long-Term Synaptic Potentiation

Science, 1988
Long-term synaptic potentiation (LTP) is a leading candidate for a synaptic mechanism of rapid learning in mammals. LTP is a persistent increase in synaptic efficacy that can be quickly induced. The biophysical process that controls one type of LTP is formally similar to a synaptic memory mechanism postulated decades ago by the ...
T H, Brown, P F, Chapman, E W, Kairiss, C L, Keenan   +3 more
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Neocortical long-term potentiation

Current Opinion in Neurobiology, 1993
LTP is a form of activity-dependent synaptic plasticity that has been investigated mainly in the hippocampus. It is considered likely that similar mechanisms may also account for aspects of naturally occurring plasticity in the neocortex. Consequently, an increasing number of studies have been devoted to the investigation of neocortical LTP.
M F, Bear, A, Kirkwood
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