Results 91 to 100 of about 2,972,786 (281)

Minimum-mass design of filamentary composite panels under combined loads: Design procedure based on a rigorous buckling analysis [PDF]

A procedure is presented for designing uniaxially stiffened panels made of composite material and subjected to combined inplane loads. The procedure uses a rigorous buckling analysis and nonlinear mathematical programing techniques.
Agranoff, N., Anderson, M. S., Stroud, W. J.   +2 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The Office for National Statistics Longitudinal Study

International Journal of Population Data Science, 2019
Background and Rationale The ONS Longitudinal Study (‘the LS’) covers England and Wales and includes individual data from the 1971 – 2011 decennial censuses and linked information on births, deaths and cancer registrations.
Alison Sizer, Oliver Duke-Williams
doaj   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Higher skeletal muscle mitochondrial oxidative capacity is associated with preserved brain structure up to over a decade

Nature Communications
Impaired muscle mitochondrial oxidative capacity is associated with future cognitive impairment, and higher levels of PET and blood biomarkers of Alzheimer’s disease and neurodegeneration.
Qu Tian, Erin E. Greig, Christos Davatzikos, Bennett A. Landman, Susan M. Resnick, Luigi Ferrucci   +5 more
doaj   +1 more source

Examining the quality and population representativeness of linked survey and administrative data: guidance and illustration using linked 1958 National Child Development Study and Hospital Episode Statistics data

International Journal of Population Data Science
Introduction Recent years have seen an increase in linkages between survey and administrative data. It is important to evaluate the quality of such data linkages to discern the likely reliability of ensuing research.
Richard Silverwood, Nasir Rajah, Lisa Calderwood, Bianca De Stavola, Katie Harron, George Ploubidis   +5 more
doaj   +1 more source

Waiting to inhale: factors associated with healthcare workers’ fears of occupationally-acquired tuberculosis (TB)

BMC Infectious Diseases, 2019
Background Fear of TB infection is rooted in historical and social memories of the disease, marked by stigma, segregation and exclusion. Healthcare workers (HCWs) face these same fears today, and even seek to hide their TB status when infected.
Michelle Engelbrecht, Asta Rau, Gladys Kigozi, André Janse van Rensburg, Edwin Wouters, Nina Sommerland, Caroline Masquillier, Kerry Uebel   +7 more
doaj   +1 more source

Longitudinal validity of spirometers--a challenge in longitudinal studies. [PDF]

, 2005
Pulmonary function testing (PFT) in longitudinal studies involves the repeated use of spirometers over long time periods. We assess the comparability of PFT results taken under biologic field conditions using thirteen certified devices of various ...
Ackermann-Liebrich, U., Brändli, O., Keidel, D., Keller, R., Kuna-Dibbert, B., Künzli, N., Leuenberger, P., Schindler, C., Schweinzer, K.M.   +8 more
core  

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Patterns of physical activity in hunter-gatherer children compared with US and UK children

Scientific Reports
Contemporary hunter-gatherers are highly active, but little is known about physical activity levels in hunter-gatherer children. We analysed 150 days of accelerometer data from 51 BaYaka hunter-gatherer children (aged 3–18) in the Republic of Congo ...
Luke Kretschmer, Mark Dyble, Nikhil Chaudhary, David Bann, Gul Deniz Salali   +4 more
doaj   +1 more source