Results 81 to 90 of about 14,354,496 (289)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Social-biological transitions: how does the social become biological? [PDF]

open access: yes, 2013
The present discussion paper sets forward a model within the life course perspective of how the social becomes biological.  The model is intended to provide a framework for thinking about such questions as how does social class get into the molecules ...
d'Errico, Angelo,   +9 more
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

The role of attitudes and behaviours in explaining socio-economic differences in attainment at age 11 [PDF]

open access: yes, 2011
This paper explores the correlates of the socio-economic gradient in children’s educational performance through the primary school years. Thus it sits between the companion papers on pre-school cognitive outcomes and attainment in the secondary school ...
Washbrook, Elizabeth   +3 more
core   +1 more source

1970 British Cohort Study: Age 29, Sweep 6, 1999-2000

open access: yes, 2007
copyright UK Data Service and data collection copyright owner.The 1970 British Cohort Study (BCS70) is a longitudinal birth cohort study, following a nationally representative sample of over 17,000 people born in England, Scotland and Wales in ...
University of London, Institute of Education, Centre for Longitudinal Studies
core   +3 more sources

Predictors of mental health help-seeking among Polish people living in the United Kingdom

open access: yesBMC Health Services Research, 2018
Background Migration has been shown to be associated with negative mental health outcomes. Moreover, migrants tend to underutilise mental health services.
Dawid Gondek, James B. Kirkbride
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Parental criminality and children’s family-life trajectories: Findings for a mid-20th century cohort [PDF]

open access: yes, 2015
The paper analyses the family life courses of sons and daughters from families with low socioeconomic status and at high risk to offend. For this Dutch cohort (N=522), born on average in 1932, register and archive data on offending and family-life events
Bijleveld, Catrien C   +3 more
core   +1 more source

National Child Development Study: Age 42, Sweep 6 Geographical Identifiers, 1999-2000: Secure Access

open access: yes, 2016
copyright UK Data Service and data collection copyright owner.The National Child Development Study (NCDS) is a continuing longitudinal study that seeks to follow the lives of all those living in Great Britain who were born in one particular ...
University of London, Institute of Education, Centre for Longitudinal Studies
core   +3 more sources

Gut Microbiota Affects Age-Related Plasma Metabolites

open access: yesMicroorganisms
Older age is a well-established risk factor for many chronic diseases, yet the biological mechanisms underlying this increased risk are not fully understood.
Jayanta K. Das   +5 more
doaj   +1 more source

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