Results 81 to 90 of about 46,178,416 (381)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Screening for psychological distress in childhood and mental health-related hospital attendance among young adults

International Journal of Population Data Science
Objectives The prevalence of mental disorders is high and increasing among children and young people. Investigating the relationship between self-reported poor mental health and mental health service utilisation can provide evidence on the benefits of ...
Gergo Baranyi, Katie Harron, Nasir Rajah, Emla Fitzsimons   +3 more
doaj   +1 more source

Development of the early axon scaffold in the rostral brain of the small spotted cat shark (Scyliorhinus canicula) embryo [PDF]

, 2014
International audienceThe cat shark is increasingly used as a model for Chondrichthyes, an evolutionarily important sister group of the bony vertebrates that include teleosts and tetrapods.
Schubert, Frank, Ware, Michelle, Waring, Colin   +2 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Families as catalysts for peer adherence support in enhancing hope for people living with HIV/AIDS in South Africa

Journal of the International AIDS Society, 2014
Introduction Hope is an essential dimension of successful coping in the context of illnesses such as HIV/AIDS, because positive expectations for the future alleviate emotional distress, enhance quality of life and have been linked to the capacity for ...
Caroline Masquillier, Edwin Wouters, Dimitri Mortelmans, Frederik le Roux Booysen   +3 more
doaj   +1 more source

Variability and agreement of frailty measures and risk of falls, hospital admissions and mortality in TILDA

Scientific Reports, 2022
Little is known about the within-person variability of different frailty instruments, their agreement over time, and whether use of repeat assessments could improve the strength of associations with adverse health outcomes.
Dani J. Kim, M. Sofia Massa, Robert Clarke, Siobhan Scarlett, Aisling M. O’Halloran, Rose Anne Kenny, Derrick Bennett   +6 more
doaj   +1 more source

Studies of transverse and longitudinal relaxations of $^{55}$Mn in molecular cluster magnet Mn$_{12}$Ac [PDF]

, 2002
The transverse and longitudinal relaxation rates 1/$T_2$ and 1/$T_1$ of $^{55}$Mn in molecular cluster magnet Mn$_{12}$Ac have been measured al low temperatures down to 200mK and in the fields upto 9T.
A. Caneschi, A. Lascialfari, A. Lascialfari, A. Robinson, A.L. Barra, C. Sangregorio, F. Hartman-Boutron, I. Chiorescu, I. Mirebeau, I. Tupitsyn, J. Villain, J. Villan, J.R. Friedman, J.R. Klander, Kunio Awaga, L. Thomas, P. Politi, P.W. Andrew, R. Sessoli, R. Sessoli, T. Goto, T. Kohmoto, T. Koshiba, T. Kubo, T. Lis, T. Pohjola, Takao Goto, Takeji Kubo, Takeshi Koshiba, W. Wernsdorfer, Y. Furukawa   +30 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Searching for a mitochondrial root to the decline in muscle function with ageing

Journal of Cachexia, Sarcopenia and Muscle, 2018
Sarcopenia, the age‐related loss of muscle mass and strength, is linked to a range of adverse outcomes, such as impaired physical performance, cognitive function, and mortality. Preventing sarcopenia may reduce the burden of functional decline with aging
Marta Gonzalez‐Freire, Fatemeh Adelnia, Ruin Moaddel, Luigi Ferrucci   +3 more
doaj   +1 more source