Results 101 to 110 of about 2,208 (185)

Research progress on application of novel isothermal amplification technology in waterborne pathogens detection

open access: yes环境与职业医学
Water resources are crucial for environmental protection and the health of humans, plants, and animals. Contamination of water by pathogens such as bacteria, viruses, and protozoa can lead to outbreaks of various water-related infectious diseases, posing
Fubin HUANG, Eryi SHU, Hongliang FAN
doaj   +1 more source

Carbon‐Modified SnS2/g‐C3N4 S‐Scheme Heterostructure with Enhanced Interfacial Charge Transfer for Efficient Photocatalytic Reduction of Cr(VI) and 4‐Nitrophenol

open access: yesSmall, EarlyView.
The S‐scheme of SnS2‐C/g‐C3N4 heterostructure enables Photocatalytic Cr(VI) and 4‐NP reduction. ABSTRACT Hexavalent chromium (Cr(VI)) and 4‐nitrophenol (4‐NP) are persistent and highly toxic water pollutants that require efficient treatment under mild conditions. In this work, L‐cysteine‐derived carbon‐modified SnS2 (SnS2‐C) was prepared hydrothermally
Dhayanantha Prabu Jaihindh   +8 more
wiley   +1 more source

Rapid detection of Mycoplasma pneumonia by Loop mediated isothermal amplification (LAMP)

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2015
Background and Objective: Mycoplasma pneumoniae bacteria, is one of the most important factor in causing of respiratory infections. Serological and molecular detection methods have their own limitation.
Davudi-Asl F   +2 more
doaj  

Conversion‐Type Anodes: Challenges, Mitigation Strategies, and Evaluation Guidelines

open access: yesSmall, EarlyView.
Conversion‐type anodes offer high theoretical capacity but exhibit coupled electrochemical, interfacial, mechanical, and transport limitations that complicate performance interpretation. A practical evaluation framework is presented to distinguish intrinsic reaction chemistry from electrode‐scale effects through complementary diagnostics and ...
Sunhyun Hwang, Won‐Sub Yoon
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

open access: yesSmart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin   +10 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

open access: yesVIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi   +5 more
wiley   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

open access: yesThe FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti   +11 more
wiley   +1 more source

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