Results 221 to 230 of about 25,138 (263)
Some of the next articles are maybe not open access.
Loop Diuretics in the Treatment of Hypertension
Current Hypertension Reports, 2016Loop diuretics are not recommended in current hypertension guidelines largely due to the lack of outcome data. Nevertheless, they have been shown to lower blood pressure and to offer potential advantages over thiazide-type diuretics. Torsemide offers advantages of longer duration of action and once daily dosing (vs.
Samuel J Mann, Mann Samuel J
exaly +3 more sources
Otolaryngologic Clinics of North America, 1993
The loop diuretics are drugs that increase the excretion of water and electrolytes in the urine by their action on the cells in the loop of Henle. Clinical reports of ototoxicity of these agents are reviewed, and the results of a number of studies in experimental animals are discussed.
openaire +2 more sources
The loop diuretics are drugs that increase the excretion of water and electrolytes in the urine by their action on the cells in the loop of Henle. Clinical reports of ototoxicity of these agents are reviewed, and the results of a number of studies in experimental animals are discussed.
openaire +2 more sources
Torsemide: A new loop diuretic
American Journal of Health-System Pharmacy, 1995The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of torsemide are reviewed. Torsemide belongs to the pyridine-sulfonylurea class of loop diuretics. Its primary site of activity is the thick ascending limb of the loop of Henle, where it blocks active reabsorption of sodium and chloride, resulting in ...
S F, Fowler, K M, Murray
openaire +2 more sources
Azosemide, a “loop” diuretic, and furosemide
Clinical Pharmacology & Therapeutics, 1979Azosemide is a new monosulfamyl diuretic which inhibits solute transport throughout the thick ascending limb of the loop of Henle. This study compared equal amounts of azosemide and furosemide (20, 40, and 80 mg) in normal subjects. No differences occurred at any dose in volume, sodium, or chloride excretion when analyzed as cumulative excretion at 4 ...
D C, Brater, S A, Anderson, S, Strowig
openaire +2 more sources
Bumetanide, a new loop diuretic
Clinical Pharmacology & Therapeutics, 1976The effect of bumetanide on renal function has been compared with that o.ffurosemide and a placebo in a double‐blind study in 9 healthy young men. The sequence for oral administration of the drug was subjected to a random assignation based upon the Latin‐square methodology under three different conditions.
S. Carrière +4 more
openaire +2 more sources
Effects of Ototoxic Diuretics (Loop Diuretics) on the Endolymphatic Sac
ORL, 2010The acute and chronic effects of treatment with ethacrynic acid (EA) and furosemide (FU) on the structure of the murine endolymphatic sac were studied by means of light and transmission electron microscopy. The animals were treated with loop diuretics in doses which are known to cause morphological alterations of the stria vascularis and a significant ...
C, Erwall +3 more
openaire +2 more sources
Loop diuretics in heart failure
Heart Failure Reviews, 2011Congestion is a major component of the clinical syndrome of heart failure, and diuretic therapy remains the cornerstone of congestion management. Despite being widely used, there is very limited evidence from prospective randomized studies to guide the prescription and titration of diuretics.
openaire +2 more sources
Clinical Pharmacology of Loop Diuretics
Drugs, 1991The clinical pharmacology of torasemide, bumetanide, piretanide and furosemide (frusemide) is discussed. These drugs share a similar mechanism of action in inhibiting Na(+)-K(+)-2Cl- reabsorption at the thick ascending limb of the loop of Henle. They differ in their routes of metabolism, pharmacokinetics, and potency.
openaire +2 more sources