Results 61 to 70 of about 22,601 (285)

Racecadotril for acute diarrhoea in children: systematic review and meta-analyses [PDF]

open access: yes, 2015
OBJECTIVE Racecadotril is an antisecretory agent that can prevent fluid/electrolyte depletion from the bowel as a result of acute diarrhoea, without affecting intestinal motility. An up-to-date systematic review is indicated to summarise the evidence on
Alam   +31 more
core   +1 more source

Fecal incontinence: the quality of reported randomized, controlled trials in the last ten years. [PDF]

open access: yes, 2008
This study was designed to analyze the characteristics and the quality of reporting of randomized, controlled trials published during the last ten years on fecal ...
Chelvanayagam, Sonya   +2 more
core   +1 more source

Loperamide Induced Life Threatening Ventricular Arrhythmia

open access: yesCase Reports in Cardiology, 2016
Loperamide is over-the-counter antidiarrheal agent acting on peripherally located μ opioid receptors. It is gaining popularity among drug abusers as opioid substitute. We report a case of a 46-year-old male that was presented after cardiac arrest.
Ankit Upadhyay   +6 more
doaj   +1 more source

Loperamide Inhibits Tachykinin NK3-Receptor-Triggered Serotonin Release Without Affecting NK2-Receptor-Triggered Serotonin Release From Guinea Pig Colonic Mucosa

open access: yesJournal of Pharmacological Sciences, 2005
The effect of loperamide on tachykinin NK2- and NK3-receptor-mediated 5-HT outflow from guinea pig colonic mucosa was investigated in vitro. The selective tachykinin NK2-receptor agonist [β-Ala8]-neurokinin A4–10 (βAla-NKA) or the selective NK3-receptor ...
Shu-ichi Kojima   +2 more
doaj   +1 more source

Antidiarrheal action of Zataria multiflora hydroalcoholic and hexane extracts in mice [PDF]

open access: yes, 2017
Introduction: Zataria multiflora Boiss. is an indigenous herbal plant found in many parts of Iran. This herb is traditionally used as a remedy for treating gastrointestinal disorders including diarrhea.
Asghari, Gholamreza.   +2 more
core   +2 more sources

Xiao Cheng Qi Decoction, an Ancient Chinese Herbal Mixture, Relieves Loperamide-Induced Slow-Transit Constipation in Mice: An Action Mediated by Gut Microbiota

open access: yesPharmaceuticals
Xiao Cheng Qi (XCQ) decoction, an ancient Chinese herbal mixture, has been used in treating slow-transit constipation (STC) for years. The underlying action mechanism in relieving the clinical symptoms is unclear.
Amanguli Tuohongerbieke   +8 more
semanticscholar   +1 more source

Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]

open access: yes, 2015
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen   +5 more
core   +2 more sources

Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose

open access: yesClinical Practice and Cases in Emergency Medicine, 2019
Loperamide is an inexpensive, over-the-counter antidiarrheal agent with emerging reports of overdose due to its opioid properties. Although it is considered by many patients to be safe, cardiotoxicity has been reported, prompting the United States Food ...
Kasha Bornstein   +2 more
doaj   +1 more source

Paeoniflorin Improved Constipation in the Loperamide-Induced Rat Model via TGR5/TRPA1 Signaling-Mediated 5-Hydroxytryptamine Secretion

open access: yesEvidence-Based Complementary and Alternative Medicine, 2021
Slow transit constipation (STC) is a common type of constipation with a high incidence rate and a large number of patients. We aimed to investigate the therapeutic effects and potential mechanism of paeoniflorin (PAE) on loperamide-induced Sprague Dawley
Yu Zhan   +6 more
semanticscholar   +1 more source

Loperamide-Induced Ventricular Tachycardia Storm

open access: yesAvicenna Journal of Medicine, 2022
Loperamide is an over-the-counter antilaxative medication with minor opioid properties. For this reason, it has recently become a drug of concern for the Food and Drug Administration due to its potential for abuse.
William Giesing   +4 more
doaj   +1 more source

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