Results 71 to 80 of about 17,797 (277)
When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
British Journal of Haematology, EarlyView.Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan +2 more
wiley +1 more source
The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea. [PDF]
, 2019 PurposeDiarrhea is recognized as a common adverse event associated with tyrosine kinase inhibitors (TKIs), with those targeting the ErbB family of receptors being associated with the highest rate of diarrhea.MethodsThis paper reviews data on the ...
Bosserman, Linda +6 more
core
Loperamide in severe protracted diarrhoea. [PDF]
Archives of Disease in Childhood, 1983 Six infants with severe life-threatening protracted diarrhoea were treated with loperamide. Steady-state perfusion studies of the jejunum showed that in 2 of them the small intestine was in a net secretory state with respect to water, and in the others this was inferred from the fact that the diarrhoea persisted despite nothing by mouth.
B K Sandhu +3 more
openaire +3 more sources
Clinical Obesity, EarlyView.ABSTRACT Bariatric surgery is the most clinically‐ and cost‐effective intervention for severe obesity. However, without adequate follow‐up, it can lead to nutritional deficiencies. Patients require life‐long nutritional supplements and follow‐up to prevent nutritional deficiencies from developing.
Sophie Haughton +2 more
wiley +1 more source
Health Information &Libraries Journal, EarlyView.Abstract Background Clinical question services offer evidence‐based relevant clinical information allowing health professionals to obtain answers in a timely manner. Objectives To explore the use and usefulness of Preevid, an evidence‐based answering service for clinical questions, among health workers during the COVID‐19 pandemic.
Concepción Rosa‐García +6 more
wiley +1 more source
Presence of the ABCB1 (MDR1) deletion mutation causing ivermectin hypersensitivity in certain dog breeds in Belgium [PDF]
, 2009 Hypersensitivity to ivermectin and certain other drugs in Collies and related breeds is caused by a 4-base pair deletion mutation in the ABCB1 gene, better known as the MDR1 gene, encoding P-glycoprotein.
Daminet, Sylvie +9 more
core +2 more sources
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang +3 more
wiley +1 more source
P-glycoprotein and its role in drug-drug interactions [PDF]
, 2014 Efflux transporters such as P-glycoprotein play an important role in drug transport in many organs. In the gut, P-glycoprotein pumps drugs back into the lumen, decreasing their absorption. Drugs which induce P-glycoprotein, such as rifampicin, can reduce
Finch, Andrew, Pillans, Peter
core +1 more source
Journal of Pharmacopuncture, 2009 Objectives : The purpose of this study was to compare the effect of acpuncture and electro-acupuncture of low(EA(L)) and high(EA(H)) frequency at Haegye(ST41) on intestinal hypomotility induced with loperamide in rats.
Lee Sang-mi, Lee Hyun
doaj +1 more source
Journal of Intellectual Disability Research, EarlyView.ABSTRACT Introduction People with intellectual disability (ID) face increased vulnerability to addictive behaviours, yet effective interventions are under‐researched. This study aimed to systematically review existing interventions for substance use and problem gambling in this population. Methods Following PRISMA guidelines, we searched Web of Science,
Amalia Udeanu +5 more
wiley +1 more source