Results 71 to 80 of about 23,058 (301)
PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide
JPGN Reports, EarlyView.Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley +1 more source
PLoS ONE, 2021 Constipation is a common condition that affects individuals of all ages, and prolonged constipation needs to be prevented to avoid potential complications and reduce the additional stress on individuals with pre-medical conditions.
Seon-Ah Park +7 more
semanticscholar +1 more source
Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. [PDF]
, 2018 The intrinsic efficacy of orthosteric ligands acting at G-protein-coupled receptors (GPCRs) reflects their ability to stabilize active receptor states (R*) and is a major determinant of their physiological effects.
Livingston, Kathryn E +4 more
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin +8 more
wiley +1 more source
Effects of probiotics on loperamide-induced constipation in rats
Scientific Reports, 2021 The role of probiotics in mitigating constipation, gut immunity, and gut microbiota has not been well studied. We aimed to evaluate the effects of probiotics on loperamide (LP)-induced constipation in Sprague–Dawley rats.
T. Inatomi, Mihoko Honma
semanticscholar +1 more source
Evaluation of the antidiarrhoeal and antidiabetic activities of the leaf aqueous extract of Syzygium cordatum hoscht. ex C.Krauss (Mytraceae) in rodents [PDF]
, 2013 Syzygium cordatum Hoscht. ex C.Krauss is widely used by traditional medicine practitioners to treat many ailments including diarrhoea and diabetes.
Amabeoku, G.J., Deliwe, M.
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner +10 more
wiley +1 more source
Ventricular fibrillation due to overdose of loperamide, the “poor man’s methadone”
Journal of Community Hospital Internal Medicine Perspectives, 2017 Loperamide is an over-the-counter antidiarrheal agent that is considered by many patients to be safe, but has been used as a drug of abuse due to its opioid properties.
Amr Salama +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Increasing researches have confirmed the relationship between slow-transit constipation and gut microbiota dysbiosis. Many population and animal experiments have identified probiotics as effectors for the relief of constipation symptoms, but the specific
Gang Wang +9 more
semanticscholar +1 more source
A case report on the long‐term use of teduglutide in a pediatric patient with short bowel syndrome
Nutrition in Clinical Practice, EarlyView.Abstract Short bowel syndrome (SBS) is the leading cause of intestinal failure, frequently necessitating long‐term parenteral nutrition (PN). Teduglutide (TED), a glucagon‐like peptide‐2 analog, has demonstrated efficacy in reducing PN dependence in both adults and children. However, long‐term data in pediatric populations remain limited.
Tsuyoshi Sakurai +8 more
wiley +1 more source