Loratadine disrupts cardiovascular and swim bladder development in zebrafish
Ecotoxicology and Environmental SafetyThe widespread presence of antihistamines such as loratadine in aquatic environments poses emerging ecotoxicological concerns, yet their developmental impacts remain poorly characterized.
Xiuyan He, Wenji Hu, Yao Zu
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Pharmacology of antihistamines
Indian Journal of Dermatology, 2013 H 1- antihistamines, the mainstay of treatment for urticaria, were developed from anticholinergic drugs more than 70 years ago. They act as inverse agonists rather than antagonists of histamine H 1 -receptors which are members of the G-protein family ...
Martin K Church, Diana S Church
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PharmaceuticsBackground: Formulating poorly water-soluble drugs poses significant challenges due to their limited solubility and bioavailability. Loratadine (LTD), classified as a BCS II molecule, exhibits notably low solubility, leading to reduced bioavailability ...
Alhasan A. Jabbar +5 more
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Vestnik Dermatologii i Venerologii, 2017 Goal of the study. To compare the efficacy of antihistamine drugs for the therapy of chronic urticaria taking into consideration their effect on the patients’ cognitive functions. Materials and methods.
O. V. Skorokhodkina, S. V. Klyucharyova
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Comparative effects of loratadine and terfenadine in the treatment of chronic idiopathic urticaria.
, 1990 Loratadine is a new selective peripheral histamine H1-receptor antagonist, that is orally effective, long-acting, and devoid of significant central and autonomic nervous system activity.
Belaich, S +6 more
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Loratadine as an Anti-inflammatory Agent Against Clostridium difficile Toxin B. [PDF]
BACKGROUND: Clostridium difficile infection (CDI) is a debilitating nosocomial infection. C. difficile produces toxins A and B, which cause inflammation. Existing therapies have issues with recurrence, cost, and safety.
Chupina Estrada, Andrea +8 more
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Validasi Metode Analisis Penetapan Kadar Campuran Loratadine dan Pseudoefedrin - HCI dalam Kapsul 'X' SR Secara Kromatografi Cair Kinerja Tinggi (KCKT) [PDF]
, 2012 Telah dilakukan penelitian validasi metode analisis penetapan kadar campuran Loratadine dan Pseudoefedrin-HCl dalam kapsul “X” SR (Sustained Release) secara Kromatografi Cair Kinerja Tinggi (KCKT).
., Tanti
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Amelioration of acetic acid-induced ulcerative colitis in rats by cetirizine and loratadine via regulation of the PI3K/Akt/Nrf2 signalling pathway and pro-inflammatory cytokine release [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Ulcerative colitis is a chronic inflammatory bowel disease (IBD) that causes inflammation and ulcers in the rectum and the innermost layer of the large intestine.
Gihan Asaad, Rasha Mostafa
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Inhibition of hypertonic saline induced cough by Loratadine in nonasthmatic patients with chronic cough [PDF]
, 2008 We examined the effect of loratadine（ 10mg） on the number of coughs induced by ultrasonically nebulized hypertonic saline in nine patients with chronic cough and in ten normal volunteers using a randomized， double- blind cross-over method.
TANAKA, Shigehiro +11 more
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Development of Co-Amorphous Loratadine–Citric Acid Orodispersible Drug Formulations
, 2022 This study aimed at the preparation and characterization of co-amorphous loratadine–citric acid orally disintegrating dosage forms (ODx). A co-amorphous loratadine–citric acid was prepared by solvent evaporation method in three different ...
Nicoleta Todoran +5 more
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