Results 101 to 110 of about 42,220 (210)

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

Experimental Physiology, Volume 111, Issue 3, Page 1524-1542, 1 March 2026.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted, Alex Aupetit, Karl Björling, Kristian Agmund Haanes, Susanne Syberg, Niklas Rye Jørgensen, Blanca I. Aldana, Hirotsugu Tsuchimochi, Mark T. Waddingham, Kristine Freude, James Todd Pearson, Lars Jørn Jensen   +11 more
wiley   +1 more source

Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

bioRxiv, 2017
Renin-angiotensin system (RAS) is commonly associated to peripheral fluid homeostasis and cardiovascular function, but recent evidence has also drawn its functional role in the brain.
C. Diniz, P. Casarotto, S. M. Fred, C. Biojone, E. Castrén, S. Joca   +5 more
semanticscholar   +1 more source

Effects of Losartan on Capillary Density in Cardiac Muscles of Diabetic Rats

مجله دانشکده پزشکی اصفهان, 2012
Background: Stimulatory and/or inhibitory effects of angiotensin II is attributed to angiotensin receptor I. A few studies investigated the role of angiotensin receptor I on cardiovascular system in diabetic subjects.
Ali Reza Fallahzadeh, Noushin Afsharmoghaddam, Majid Khazaei   +2 more
doaj  

Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats

Journal of Applied Oral Science
Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats.
Gabriel Mulinari-Santos, Jaqueline Silva dos Santos, Letícia Pitol Palin, Ana Cláudia Ervolino da Silva, Cristina Antoniali, Leonardo Perez Faverani, Roberta Okamoto   +6 more
doaj   +1 more source

Optimizing Blood Pressure Control: A Randomized Comparative Trial of Losartan/Chlorthalidone vs. Losartan/Hydrochlorothiazide

Cardiology and Therapy
Introduction Cardiovascular diseases are a leading cause of global mortality, with hypertension as a major risk factor. Low control rates are often attributed to monotherapy, while evidence and clinical guidelines support the effectiveness of combination
Isabel E. Rucker-Joerg, Ernesto G. Cardona-Muñoz, Francisco G. Padilla-Padilla, Rodrigo Suarez-Otero, Yulia Romero-Antonio, Emmanuel Canales-Vázquez, Kevin F. Rios-Brito, Ileana C. Rodríguez-Vazquez, Jorge González-Canudas   +8 more
doaj   +1 more source

Topical losartan to prevent stromal scarring during post-cross-linking infection in pediatric keratoconus: A case report. [PDF]

Am J Ophthalmol Case Rep
Barzaghi F, Kronschläger M, Amir-Asgari S, Findl O.   +3 more
europepmc   +1 more source

Drug-Induced Liver Injury Associated With the Angiotensin II Receptor Blocker Losartan in a 59-Year-Old Woman With Hypertension: A Case Report. [PDF]

Am J Case Rep
Al-Ajaj A, Melki W.
europepmc   +1 more source

Current Status of Research on Losartan in Tumour Therapy. [PDF]

J Cell Mol Med
Wang H, Yuan S, Wang H.
europepmc   +1 more source

Losartan Alleviates Chemical Burn-Induced Limbal Stem Cell Deficiency: Repurposing a Venerable Anti-Hypertension Drug. [PDF]

Invest Ophthalmol Vis Sci
Foroozandeh P, Kaplan N, Xu D, Qi X, Kayaalp-Nalbant E, Miller SD, Lu KQ, Lavker RM, Peng H.   +8 more
europepmc   +1 more source

Losartan-induced Angioedema: A Case Report and Review of Literature. [PDF]

J Community Hosp Intern Med Perspect
Tou LC, Nourse A, Cox R, Stanford S.
europepmc   +1 more source