Results 81 to 90 of about 31,170 (214)
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Losartan in Marfan syndrome [PDF]
Marfan syndrome (MFS) is a multisystemic disorder of the connective tissue with a prevalence of 1 per 5000 and is caused by mutations in the FBN1 gene.
den Hartog, A.W.
core +1 more source
Natural History of Chronic Kidney Disease in Sickle Cell Disease
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley +1 more source
There is no cure or beneficial management option for Limb-Girdle muscular dystrophy (MD) type 2B (LGMD2B). Losartan, a blood pressure (BP) lowering angiotensin II (AngII) receptor type 1 (ATR1) blocker (ARB) with unique anti-transforming growth factor-β (
Zoe White +6 more
doaj +1 more source
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Voclosporin‐induced gingival enlargement: A case report
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca +2 more
wiley +1 more source
Ola Granström,1 Lars-Åke Levin,2 Martin Henriksson11AstraZeneca Nordic, Södertälje, 2Center for Medical Technology Assessment, Linköping University, Linköping, SwedenBackground: Although angiotensin ...
Levin LA +2 more
core
ABSTRACT Hemolacria is a rare condition characterized by bloody tears. Its etiology is often multifactorial, but functional/psychosomatic mechanisms have been proposed when organic causes are excluded. A 48‐year‐old woman with a history of multiple traumatic brain injuries (coma in 2008, car accident in 2017) presented with refractory generalized ...
Roghayeh Mohammadi, Ahmad Alipour
wiley +1 more source
Western blots comparing losartan and water groups.
Immunoblots for pERK1/2, ERK1/2, pSmad2, pSmad3, Smad2/3 and GAPDH for 12 scleral specimen groups. (1) water control; (2) losartan control; (3) fellow eyes of water-treated glaucoma; (4) fellow eyes of losartan-treated glaucoma; (5) water-treated ...
Thao D. Nguyen (695816) +12 more
core +1 more source
ABSTRACT Peripartum cardiomyopathy (PPCM) is defined as the onset of left ventricular systolic dysfunction either during pregnancy or up to 5 months after delivery, without any other known cause of heart failure. The exact pathogenesis of this disease is unknown, and its prognosis remains poorly understood.
Muhammad Ibrahim Shah +4 more
wiley +1 more source

