PROTECTIVE EFFECTS OF LOSARTAN AGAINST ETHANOL-INDUCED LIVER INJURY: A STUDY IN MALE WISTAR RATS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut UniversityObjectives: Chronic consumption of ethanol poses serious risks to liver health, resulting in oxidative stress and inflammation that can worsen hepatic dysfunction. This research explores the protective role of losartan, an angiotensin II receptor blocker
Mahdiyeh Hedayati -Moghadam +3 more
doaj +1 more source
Protecting the ischemic heart : pharmacological protection against myocardial ischemia in rats in vivo and in vitro [PDF]
, 2004 Today in Switzerland approximately 40% of all deaths are due to cardiovascular diseases. More than half of these are due to ischemic heart disease. Among the fatal consequences of ischemic heart disease are life-threatening arrhythmias and myocardial ...
Butz, Silvia
core +1 more source
Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]
, 2012 BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Meinen, Sarina +5 more
core +1 more source
STUDY THE NEPHRO-PROTECTIVE EFFECTS OF LOSARTAN ON RATS [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2014 In the Reduction of Endpoints in NIDDM (noninsulin–dependent diabetes mellitus) with the Angiotensin II Antagonist Losartan study (RENAAL study), Losartan reduced the risk of the doubling of serum creatinine concentration by 25% and of end stage renal ...
Hosny Elewa1
doaj +1 more source
Fenofibrate and losartan [PDF]
Annals of the Rheumatic Diseases, 2003 Should we take advantage of their uricosuric properties in clinical practice? The interesting study published in this issue of the journal by Takahashi et al sheds light on two drugs, losartan and fenofibrate, which have hypouricaemic properties, in addition to their main therapeutic effects.1 Losartan potassium is an orally active angiotensin II ...
openaire +2 more sources
Pharmaceutical Biology, 2018 Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown.
Baiping Dong +3 more
doaj +1 more source
Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan. [PDF]
PLoS ONE, 2015 Exposure of platelets to collagen triggers the formation of a platelet clot. Pharmacological agents capable of inhibiting platelet activation by collagen are thus of potential therapeutic interest.
Peng Jiang +5 more
doaj +1 more source
Neuroprotective Effect of Losartan after Traumatic Brain Injury in Male Rats Based on Marmarou Model
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022 Background and Objective: Traumatic brain injury is the most important cause of death among young people in the world. Considering the neuroprotective effect of losartan on the recovery of brain damage, the present study was conducted to investigate the ...
Sh Shadi +2 more
doaj
Losartan Treatment Could Improve the Outcome of TBI Mice
Frontiers in Neurology, 2020 Traumatic brain injury frequently leads to serious mortality and physical disability, yet effective treatments remains insufficient. TBI always leads to a series of secondary brain injuries including neuronal apoptosis, continuous inflammation ...
Jianhua Xiong +7 more
doaj +1 more source
, 2023 Constructing efficient theranostic nanoparticles (NPs) to improve the therapeutic effect is a great challenge for triple-negative breast cancer (TNBC).
Ji Wu (217440) +19 more
core +1 more source