STUDY THE NEPHRO-PROTECTIVE EFFECTS OF LOSARTAN ON RATS [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2014 In the Reduction of Endpoints in NIDDM (noninsulin–dependent diabetes mellitus) with the Angiotensin II Antagonist Losartan study (RENAAL study), Losartan reduced the risk of the doubling of serum creatinine concentration by 25% and of end stage renal ...
Hosny Elewa1
doaj +1 more source
Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]
, 2012 BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Meinen, Sarina +5 more
core +1 more source
Pharmaceutical Biology, 2018 Context: Ginkgo leaf tablets (GLTs) and losartan are often simultaneously used for the treatment of hypertension in Chinese clinics. However, the herb–drug interaction between GLT and losartan is still unknown.
Baiping Dong +3 more
doaj +1 more source
Safety of losartan in hypertensive patients with thiazide-induced hyperuricemia [PDF]
, 1999 Safety of losartan in hypertensive patients with thiazide-induced hyperuricemiaBackgroundLosartan, an angiotensin II receptor antagonist, has been shown to decrease serum uric acid and to increase urinary excretion of uric acid.MethodsTo determine if ...
Carides, Alexandra D. +8 more
core +1 more source
Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes
Angewandte Chemie, EarlyView.A strategy for accelerated photochemical reaction discovery is reported that harnesses the dynamic speciation of copper complexes, driven by their labile metal–ligand bonds. This platform simplifies reaction screening by combining an earth‐abundant copper(II) salt with commercially available ligands, which reversibly generate multiple catalytic species
Alessio Regni +6 more
wiley +2 more sources
Neuroprotective Effect of Losartan after Traumatic Brain Injury in Male Rats Based on Marmarou Model
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022 Background and Objective: Traumatic brain injury is the most important cause of death among young people in the world. Considering the neuroprotective effect of losartan on the recovery of brain damage, the present study was conducted to investigate the ...
Sh Shadi +2 more
doaj
Losartan Treatment Could Improve the Outcome of TBI Mice
Frontiers in Neurology, 2020 Traumatic brain injury frequently leads to serious mortality and physical disability, yet effective treatments remains insufficient. TBI always leads to a series of secondary brain injuries including neuronal apoptosis, continuous inflammation ...
Jianhua Xiong +7 more
doaj +1 more source
Losartan: Benefits Beyond Hypertension [PDF]
, 2022 Losartan was the first angiotensin AT1 receptor blocker (ARB) approved by US Food and Drug Administration (FDA) for the treatment of hypertension. In addition to its established antihypertensive and end organ effects, several benefits of losartan beyond ...
Vikas Makkar +2 more
core
Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan. [PDF]
PLoS ONE, 2015 Exposure of platelets to collagen triggers the formation of a platelet clot. Pharmacological agents capable of inhibiting platelet activation by collagen are thus of potential therapeutic interest.
Peng Jiang +5 more
doaj +1 more source
, 2023 Constructing efficient theranostic nanoparticles (NPs) to improve the therapeutic effect is a great challenge for triple-negative breast cancer (TNBC).
Ji Wu (217440) +19 more
core +1 more source