Results 61 to 70 of about 28,228 (226)
Mechanisms of diabetic cardiomyopathy: Focus on inflammation
Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2326-2338, May 2025.Abstract Purpose of Review Type 2 diabetes (T2D) significantly increases the risk of heart failure (HF), either through the progression of coronary artery disease (CAD) or through direct myocardial alterations, termed diabetic cardiomyopathy. This review examines key pathophysiological mechanisms underlying diabetic cardiomyopathy, focusing on the role
Myriam Bellemare +5 more
wiley +1 more source
Clinical and Experimental Hypertension, 2018 The objective of the present study was to investigate the effects of single and combined administration of ramipril and losartan on renal structure and function in spontaneously hypertensive rats (SHRs). Thirty-two 9-week-old SHRs and eight Wistar-Kyoto (
Lin Yun +7 more
doaj +1 more source
Acquired Genotype‐Positive Long QT Syndrome After Pediatric Heart Transplantation
Pediatric Transplantation, Volume 29, Issue 3, May 2025.ABSTRACT Background Congenital long QT syndrome (LQTS) is rare but significant, as it carries a risk for ventricular arrhythmias and sudden cardiac death. Its diagnosis can be made clinically by serial ECGs, ambulatory ECG monitoring, and exercise stress testing; however, genetic testing is confirmatory in the majority of cases.
Nicholas V. Barresi +3 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 4, April 2025.ABSTRACT Meningococcal meningitis can lead to serious neurological complications such as hydrocephalus directly and contribute to cerebral small vessel disease indirectly, especially in patients with pre‐existing conditions like dilated cardiomyopathy.
Yousif Mohamed +3 more
wiley +1 more source
Dapsone‐Induced Heinz Body Hemolytic Anemia: A Case Report
Clinical Case Reports, Volume 13, Issue 4, April 2025.ABSTRACT Patients who develop acute anemia, without evidence of blood loss, should have a hemolysis workup including a medication review in case this could be contributing. In our patient's case, workup was significant for Heinz body hemolytic anemia due to home dapsone. Patient's anemia ultimately resolved with drug cessation.
Tyler Edwards +2 more
wiley +1 more source
Chronic Viral Infections and Al Amyloidosis: An Uncommon Association
Clinical Case Reports, Volume 13, Issue 4, April 2025.ABSTRACT AL‐amyloidosis is caused by deposition of pathological insoluble proteins in organs and tissues. HIV infection is a multi‐system disorder causing chronic inflammation. We report a case of AL‐amyloidosis associated with HIV suggesting that HIV‐associated immune dysregulation might be critical for pathogenesis of plasma cells dyscrasias and then
Alberto Palladini +7 more
wiley +1 more source
International Journal of Nephrology and Renovascular Disease, 2010 Elizabeth Ripley, Ari HirschDivision of Nephrology, Virginia Commonwealth University, Richmond, Virginia, USAAbstract: Losartan, the first AT1 receptor blocker (ARB), was FDA approved 15 years ago.During those years, researchers and clinicians have ...
Elizabeth Ripley, Ari Hirsch
doaj
Кардиоваскулярная терапия и профилактика, 2011 Aim. To assess the potential of the angiotensin II receptor antagonist losartan for the correction of hyperuricemia (HU) in patients with arterial hypertension (AH) and metabolic syndrome (MS). Material and methods.
S. V. Nedogoda +3 more
doaj +1 more source
Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy
ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo +7 more
wiley +1 more source