Results 111 to 120 of about 173,415,106 (290)

Growth rate and heterozygosity in the plaice, Pleuronectes platessa

, 1986
Samples of young plaice were examined to see if there was any relationship between growth rate and individual heterozygosity, screened across five polymorphic enzyme loci (Pgm-1, Ada, Mdh-2, Pgi-2, Gpdh-l).
B J McAndrew, Ward, Robert D, Beardmore, John A, J A Beardmore, McAndrew, Brendan, R D Ward   +5 more
core   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

Perspective on This Article from Loss of Heterozygosity (LOH) Profiles—Validated Risk Predictors for Progression to Oral Cancer

, 2012
Perspective on This Article from Loss of Heterozygosity (LOH) Profiles—Validated Risk Predictors for Progression to Oral ...
Lang Wu (540806), J. Jack Lee (9268710), Miriam P. Rosin (14873960), Michele Williams (14873939), Lewei Zhang (679120), Pamela J. Gardner (15093436), Ken Berean (14873948), Catherine F. Poh (3044727), Denise M. Laronde (13032402), Huijun Jiang (2097355)   +9 more
core   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

Supplementary Data from Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR-562

, 2009
Supplementary Data from Loss of Heterozygosity at 2q37 in Sporadic Wilms' Tumor: Putative Role for miR ...
Jenny Wegert (11600764), Micheala A. Aldred (2806378), Manfred Gessler (164045), Kylie M. Drake (14977551), Kathy Pritchard-Jones (106034), Jeffrey Dome (110537), Paul Grundy (644295), E. Cristy Ruteshouser (14913558), Rachael Natrajan (265328), Vicki Huff (440759), Phyllis Harbor (14977554), Chris Jones (25458)   +11 more
core   +1 more source

Application of Chromosomal Microarray Analysis in Genetic Reasons of Miscarriage Tissues

The Application of Clinical Genetics
Zhen Xu,1– 3 Na Liu,1– 3 Lu Gao,1– 3 Dongyi Yu1– 3 1Center for Medical Genetics and Prenatal Diagnosis, Shandong Provincial Maternal and Child Health Care Hospital, Affiliated to Qingdao University, Jinan, Shandong, 250000, People’s Republic of China ...
Xu Z, Liu N, Gao L, Yu D
doaj  

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Loss of allelic heterozygosity at the harveyras locus in human oral carcinomas

, 1991
The Harveyras locus was examined for restriction fragment polymorphism and loss of allelic heterozygosity in 62 oral cancer patients. Southern blot analysis onBamHI digests of the tumour tissue DNA, revealed 23 patients with H-ras-1 heterozygosity.
Bhoite, Leena T., Deo, Madhav G., Mehta, Ashok R., Sanghavi, Vikram, Saranath, Dhananjaya   +4 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source