Results 11 to 20 of about 138,753 (343)

Loss of heterozygosity for chromosomes 16q in Wilms tumors predicts outcomes: A meta-analysis. [PDF]

World J Gastrointest Oncol
Song YH, Li WL, Yang Z, Gao Y, Feng ZP.
europepmc   +2 more sources

9p21 Loss of Heterozygosity [PDF]

, 2020
National Cancer Institute
openalex   +2 more sources

p120 catenin is required for the stress response in Drosophila [PDF]

, 2013
p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila ...
Bauer, Christin, Stefanatos, Rhoda K., Vidal, Marcos   +2 more
core   +18 more sources

Targeting tumor vulnerabilities associated with loss of heterozygosity

Molecular & Cellular Oncology, 2020
We show that N-acetyltransferase 2 (NAT2) loss of heterozygosity can be targeted in >4% of colorectal cancers with the use of a small molecule. We identify and describe the effect of a compound that impairs the growth of colorectal tumors with slow NAT2 ...
Veronica Rendo, Ivaylo Stoimenov, Tobias Sjöblom   +2 more
doaj   +1 more source

Corticotropinoma as a Component of Carney Complex. [PDF]

, 2017
Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown.
Chittiboina, Prashant, Dimopoulos, Aggeliki, Faucz, Fabio R, Hernández-Ramírez, Laura C, Kay, Denise M, Lane, John, Lodish, Maya B, Mills, James L, Pankratz, Nathan, Stratakis, Constantine A, Tatsi, Christina, Valdés, Nuria   +11 more
core   +2 more sources

Molecular and clinicopathological analysis of three cases of gastric juvenile polyposis

JGH Open, 2022
Background and Aim Juvenile polyposis (JP) is a rare disease known to be associated with mutations either in SMAD4/BMPR1A. JP is known to often develop into malignant tumors, with a reported probability of 9–50%.
Yuya Yamashiro, Yuka Yanai, Tsutomu Takeda, Takuo Hayashi, Yoichi Akazawa, Noboru Yatagai, Hiroya Ueyama, Hidetaka Eguchi, Akihito Nagahara, Takashi Yao, Tsuyoshi Saito   +10 more
doaj   +1 more source

Pretransplant HLA typing revealed loss of heterozygosity in the major histocompatibility complex in a patient with acute myeloid leukemia [PDF]

, 2019
Introduction Chromosomal abnormalities are frequent events in hematological malignancies. The degree of HLA compatibility between donor and recipient in hematopoietic stem cell transplantation is critical.
Breman, Amy M., Britton, Rebecca M., Cui, Connie P., Farag, Sherif S., Kashi, Zahra, Krueger-Sersen, Mary, Littrell, Courtney A., Lobashevsky, Andrew L., Martin, Russ K., Singh, Susmita, Vance, Gail H.   +10 more
core   +1 more source

Molecular clonality analysis of esophageal adenocarcinoma by multiregion sequencing of tumor samples

BMC Research Notes, 2017
Background Intratumor heterogeneity has been demonstrated in several cancer types, following a model of branched evolution. It is unknown to which extent intratumor heterogeneity is applicable to esophageal adenocarcinoma. Therefore the aim of this study
Anna M. J. van Nistelrooij, Ronald van Marion, Linetta B. Koppert, Katharina Biermann, Manon C. W. Spaander, Hugo W. Tilanus, J. Jan B. van Lanschot, Bas P. L. Wijnhoven, Winand N. M. Dinjens   +8 more
doaj   +1 more source

General theory for stochastic admixture graphs and F-statistics [PDF]

, 2018
We provide a general mathematical framework based on the theory of graphical models to study admixture graphs. Admixture graphs are used to describe the ancestral relationships between past and present populations, allowing for population merges and ...
Soraggi, Samuele, Wiuf, Carsten
core   +2 more sources

High incidence of microsatellite instability and loss of heterozygosity in three loci in breast cancer patients receiving chemotherapy: a prospective study

BMC Cancer, 2012
Background The aim of the study was to evaluate potential chemotherapy-induced microsatellite instability, loss of heterozygosity, loss of expression in mismatch repair proteins and associations with clinical findings in breast cancer patients ...
Kamat Nasir, Khidhir Mohammed A, Jaloudi Mohammed, Hussain Sabir, Alashari Mouied M, Al Qawasmeh Khaled H, Rannug Ulf   +6 more
doaj   +1 more source