Results 51 to 60 of about 31,024 (202)

Lovastatin Decreases the Expression of CD133 and Influences the Differentiation Potential of Human Embryonic Stem Cells

open access: yesStem Cells International, 2016
The lipophilic statin lovastatin decreases cholesterol synthesis and is a safe and effective treatment for the prevention of cardiovascular diseases. Growing evidence points at antitumor potential of lovastatin.
Ade Kallas-Kivi   +2 more
doaj   +1 more source

The role of statin drugs in combating cardiovascular diseases –A review [PDF]

open access: yes, 2011
Statins clearly confer substantial benefit in people with established cardiovascular (CV) disease. Increased cholesterol levels have been associated with cardiovascular diseases (CVD), and statins are therefore used in the prevention of these diseases ...
Suresh Pichandi , Palanisamy Pasupathi, Y.Yagneswara Rao, Jawahar Farook, Athimoolam Ambika, Babu Shankar Ponnusha , Sathiyamoorthy Subramaniyam, Rajaram Virumandy, Boopathi subramaniyam Int J Cur Sci Res.
core  

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Lovastatin Alleviates Endothelial-to-Mesenchymal Transition in Glomeruli via Suppression of Oxidative Stress and TGF-β1 Signaling

open access: yesFrontiers in Pharmacology, 2017
Statins may decrease chronic kidney diseases (CKDs) risk, but their underlying molecular mechanisms are not completely understood. Recent studies indicate Endothelial-to-mesenchymal transition (EndMT) plays an important role contributing to renal ...
Zejun Ma   +6 more
doaj   +1 more source

IMMOBILIZATION AND APPLICATION OF PARTIAL PURIFIED LOVASTATIN PRODUCED FROM LOCAL ISOLATE ASPERGILLUS TERREUS A50 USING SOLID STATE FERMENTATION

open access: yesThe Iraqi Journal of Agricultural science, 2021
This work was designed to study the free and immobilized partial purified lovastatin in various applications. The results of HMG-CoA reductase inhibition showed enzyme inhibition at 10 mM of standard and partial purified lovastatin with specific activity
A. J. R. Al-Sa'ady, G. M. Aziz
doaj   +1 more source

Long‐term disease control of disseminated superficial actinic porokeratosis (DSAP) with simvastatin 2%/ cholesterol 2% cream

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Introduction Disseminated superficial actinic porokeratosis (DSAP) is a rare keratinization disorder associated with an increased risk of cutaneous tumors. Objectives To develop a feasible and easy‐to‐apply treatment regimen for long‐time disease control of DSAP including prevention of new skin tumors. Patients and Methods 19 patients with DSAP
Berenice M. Lang   +6 more
wiley   +1 more source

Humphrey Center News: Fall 1988 v. 3, no. 2 [PDF]

open access: yes, 1988
Newsletter of the Hubert H.
Hubert H. Humphrey Cancer Research Center of Boston University   +1 more
core  

Structure of AI Responses With Complex Patient Analysis for Patient Alternatives and Patient Modifiers

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background Artificial intelligence (AI) is already a powerful tool that is rapidly growing within the dental sector. Reports of structure and characteristics of AI responses to patient scenarios are limited. Purpose To analyse characteristics and structure of AI responses to prompts for treatment planning alternatives and patient alternatives ...
David C Johnsen   +4 more
wiley   +1 more source

Improved methanol-derived lovastatin production through enhancement of the biosynthetic pathway and intracellular lovastatin efflux in methylotrophic yeast

open access: yesBioresources and Bioprocessing, 2018
Background Methanol has attracted interest as a substrate for improvement of product titers and yields of bioprocesses, because methanol has a more reduced state than sugars do and can be renewably synthesized from abundant natural gas supplies.
Yiqi Liu   +6 more
doaj   +1 more source

Safety and Effectiveness of Glecaprevir/Pibrentasvir in Children and Adolescents With Chronic Hepatitis C: Reports From All‐Case Post‐Marketing Surveillance in Japan

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim The aim of this all‐case post‐marketing study was to evaluate the real‐world safety and effectiveness in all children and adolescents with chronic hepatitis C with or without compensated cirrhosis treated with glecaprevir/pibrentasvir (G/P) in Japan. Methods This prospective, observational post‐marketing surveillance study was conducted at
Tatsuki Mizuochi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy