Results 31 to 40 of about 17,598 (157)

Moderate Intensity Statins Plus Ezetimibe Combination Therapy Versus High Intensity Statins Monotherapy After Percutaneous Coronary Intervention: A Systematic Review and Meta‐Analysis

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
ABSTRACT Background High‐intensity statins are standard therapy after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS), yet tolerability concerns and residual cardiovascular risk remain important challenges. Moderate‐intensity statin therapy combined with ezetimibe has emerged as a potential alternative, although its ...
Emad Uddin Sajid   +12 more
wiley   +1 more source

Enhancing Lovastatin Biosynthesis in Oyster Mushrooms (Pleurotus ostreatus) using Phytohormones

open access: yes, 2023
The biosynthesis of lovastatin, the anti-cholesterol compound, in oyster mushrooms (Pleurotus ostreatus), has the potential to be enhanced by utilizing phytohormones, which activate the expression of certain genes.
Mustafa, Fransisca Astrid   +2 more
core   +1 more source

Effect of roxithromycin on the pharmacokinetics of lovastatin in volunteers

open access: yes, 2002
Objective: To investigate the influence of concomitant administration of roxithromycin on the plasma pharmacokinctics of lovastatin. Methods: In an open, randomized, crossover study, 12 healthy volunteers received 80 mg lovastatin orally either alone or ...
Kees, F., Mair, G., Bucher, M.
core   +1 more source

Targeting Brain Cholesterol Homeostasis in Alzheimer's Disease: Mechanisms and Therapeutic Perspectives

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
Brain cholesterol homeostasis is tightly regulated and largely independent of peripheral cholesterol. This review proposes a unifying framework in which aging, sex, and related biological stressors, including hypercholesterolemia, neurodegeneration, inflammation, and oxidative stress, converge to disrupt cholesterol homeostasis in the brain ...
Myuri Ruthirakuhan   +2 more
wiley   +1 more source

Improved methanol-derived lovastatin production through enhancement of the biosynthetic pathway and intracellular lovastatin efflux in methylotrophic yeast

open access: yes, 2018
Background Methanol has attracted interest as a substrate for improvement of product titers and yields of bioprocesses, because methanol has a more reduced state than sugars do and can be renewably synthesized from abundant natural gas supplies.
Yiqi Liu   +6 more
core   +1 more source

Lovastatin fermentlevek HPLC-s szennyezőprofil módszerének optimalizálása és alternatív módszerfejlesztése

open access: yes, 2017
Lovastatin fermentlevek HPLC-s szennyezőprofil módszerének fejlesztését hajtottam végre kísérlettervező szoftver segítségével. A módszer hatékonyságának növelése céljából a módszerfejlesztést UHPLC készüléken is elvégeztem.
Dürgő, Brigitta
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

APOE genotype and the effect of statins on lipid outcomes: A meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1268-1286, May 2026.
Aim APOE genotype may affect statin therapy response. We conducted a meta‐analysis to update and quantify this association across various outcomes. Methods We searched seven databases (MEDLINE, Scopus, Web of Science, the Cochrane Library, APA PsycINFO, CINAHL Plus and ClinicalTrials.gov) on 9 May 2024.
Innocent G. Asiimwe   +4 more
wiley   +1 more source

Controlled release of lovastatin from poly(lactic-co-glycolic acid) nanoparticles for direct pulp capping in rat teeth

open access: yes, 2017
Hung-Pin Lin,1,2,* Han-Ping Tu,3,* Yu-Ping Hsieh,4 Bor-Shiunn Lee3 1Department of Dentistry, MacKay Memorial Hospital, 2Department of Dentistry, School of Dentistry, National Taiwan University, 3Graduate Institute of Oral Biology, School of Dentistry ...
Tu HP, Lee BS, Hsieh YP, Lin HP
core  

Lovastatin downregulates renal myofibroblast function in vitro

open access: yes, 2002
Interstitial fibrosis is recognised as the best histological predictor of progressive renal disease. Myofibroblasts contribute to this process through several functions including hyperproliferation, collagen and collagenase synthesis and reorganisation ...
Kelynack, Kristen J.   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy