Results 21 to 30 of about 17,598 (157)

Optimization of lovastatin production from Aspergillus fumigatus

open access: yes, 2016
The present investigation, focused on screening of various fungal species for Lovastatin production using different agro-based wastes, also, for maximizing lovastatin productivity by isolated Aspergillus fumigatus using response surface methodology (RSM).
Abo Elsoud, Mostafa M.   +2 more
core   +1 more source

Primary cardiovascular preventive effect of thiazolidinedione in adults with type 2 diabetes: A nationwide cohort study in Korea

open access: yesJournal of Diabetes Investigation, EarlyView.
Among Korean adults with type 2 diabetes and no prior cardiovascular disease, thiazolidinedione use was associated with a lower risk of the primary composite outcome of stroke, myocardial infarction, hospitalization for heart failure, and all‐cause mortality compared to dipeptidyl peptidase‐4 inhibitor use. ABSTRACT Background Thiazolidinediones (TZDs)
Yun Young Choi   +4 more
wiley   +1 more source

Estudo da produção de metabólitos secundários por Monascus ruber CCT 3802 em cultivo submerso [PDF]

open access: yes, 2005
O impacto visual é elemento de decisão na escolha de um alimento e a indústria alimentícia utiliza-se de corantes para deixar os alimentos potencialmente mais atrativos.
Sá, Renata Anselmo de
core  

Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis [PDF]

open access: yes, 2007
Synergy study with chemotherapeutic agents is a common in vitro strategy in the search for effective cancer therapy. For non-chemotherapeutic agents, efficacious synergistic effects are uncommon. Here, we have examined two non-chemotherapeutic agents for
Wai S. Poon   +7 more
core   +1 more source

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

open access: yesPeriodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Lovastatin protects against experimental plague in mice.

open access: yes, 2010
BACKGROUND: Plague is an ectoparasite-borne deadly infection caused by Yersinia pestis, a bacterium classified among the group A bioterrorism agents. Thousands of deaths are reported every year in some African countries.
Nappez Claude   +9 more
core   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez   +6 more
wiley   +1 more source

Reappraisal Of G1‐Phase Arrest And Synchronization By Lovastatin [PDF]

open access: yes, 2002
It has been proposed that lovastatin arrests cells in the G1‐phase of the division cycle, and that release from lovastatin inhibition produces a synchronized culture.
Cooper, Stephen
core   +1 more source

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias   +7 more
wiley   +1 more source

Dual Effects for Lovastatin in Anaplastic Thyroid Cancer: The Pivotal Effect of Transketolase (Tkt) on Lovastatin and Tumor Proliferation

open access: yes, 2018
This study tested the hypothesis that the effects of lovastatin on anaplastic thyroid cancer cell growth are mediated by upregulation of transketolase (TKT) expression.
Chih-Yuan Wang   +2 more
core   +1 more source

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