Results 61 to 70 of about 1,208,187 (262)

Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

Journal of Lipid Research, 1990
We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor.
JC Khoo, E Miller, P McLoughlin, D Steinberg   +3 more
doaj  

Carbamylated low-density lipoprotein induces endothelial dysfunction.

European Heart Journal, 2014
AIMS Cardiovascular events remain the leading cause of death in Western world. Atherosclerosis is the most common underlying complication driven by low-density lipoproteins (LDL) disturbing vascular integrity.
T. Speer, F. Owala, E. Holy, S. Zewinger, Felix L Frenzel, B. Stähli, M. Razavi, S. Triem, Hrvoje Cvija, L. Rohrer, Sarah Seiler, G. Heine, V. Jankowski, J. Jankowski, G. Camici, A. Akhmedov, D. Fliser, T. Lüscher, F. Tanner   +18 more
semanticscholar   +1 more source

Plasma low density lipoproteins [PDF]

Nature, 1977
Low Density Lipoproteins. Edited by C. E. Day and R. S. Levy. Pp. xx + 445. (Plenum: New York and London, 1977). $47.40.
openaire   +2 more sources

Relation between insulin resistance and fast-migrating LDL subfraction as characterized by capillary isotachophoresis

Journal of Lipid Research, 2005
The proportion of the electronegative low density lipoprotein [LDL(−)] subfraction, which is atherogenic, is increased in type 2 diabetes but is not reduced by glycemic control.
Bo Zhang, Takuya Kaneshi, Takao Ohta, Keijiro Saku   +3 more
doaj  

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein

Journal of Cell Biology, 1984
Acetylated-low density lipoprotein (Ac-LDL) is taken up by macrophages and endothelial cells via the "scavenger cell pathway" of LDL metabolism. In this report, aortic and microvascular endothelial cells internalized and degraded 7-15 times more [125I ...
J. Voyta, D. P. Via, C. E. Butterfield, B. Zetter   +3 more
semanticscholar   +1 more source

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells.

Proceedings of the National Academy of Sciences of the United States of America, 1990
After exposure to low density lipoprotein (LDL) that had been minimally modified by oxidation (MM-LDL), human endothelial cells (EC) and smooth muscle cells (SMC) cultured separately or together produced 2- to 3-fold more monocyte chemotactic activity ...
S. D. Cushing, J. A. Berliner, Anthony J. Valente, M. Territo, M. Navab, F. Parhami, Ross G. Gerrity, C. Schwartz, A. Fogelman   +8 more
semanticscholar   +1 more source

Intracellular trafficking of pigeon β-very low density lipoprotein and low density lipoprotein at low and high concentrations in pigeon macrophages

Journal of Lipid Research, 2000
Foam cell formation occurs in vitro at lipoprotein concentrations above 50 μg/ml in pigeon macrophages. Hypothetically, intracellular trafficking of lipoproteins at higher concentrations may differ from uptake of lipoproteins associated with low ...
Nancy L. Jones, Jerry A. Saunders, Revill R. Mallory   +2 more
doaj  

Role of oxidised low density lipoprotein in atherogenesis.

British heart journal, 1993
Overview of the concept ofoxidative modification ofLDL There can be no doubt now that there is a continuum of increasing risk for complications ofatherosclerosis when plasma cholesterol levels exceed 160-180 mg/dl. Many types of experimental and clinical
J. Witztum
semanticscholar   +1 more source

Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells: inhibition of cholesterol esterification by oxidatively modified low density lipoprotein.

Journal of Lipid Research, 1989
The rate of degradation of oxidatively modified low density lipoprotein (Ox-LDL) by human endothelial cells was similar to that of unmodified low density lipoprotein (LDL), and was approximately 2-fold greater than the rate of degradation of acetylated ...
I Jialal, A Chait
doaj  

Electronegative LDLs from familial hypercholesterolemic patients are physicochemically heterogeneous but uniformly proapoptotic

Journal of Lipid Research, 2007
A highly electronegative fraction of human plasma LDLs, designated L5, has distinctive biological activity that includes induction of apoptosis in bovine aortic endothelial cells (BAECs).
Hsin-hung Chen, Brian D. Hosken, Max Huang, John W. Gaubatz, Christine L. Myers, Ronald D. Macfarlane, Henry J. Pownall, Chao-yuh Yang   +7 more
doaj