Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure [PDF]
Frontiers in NeurologyIntroductionMany Veterans who experienced blast-related traumatic brain injuries (TBIs) in Iraq and Afghanistan currently suffer from chronic cognitive and mental health problems that include depression and post-traumatic stress disorder (PTSD).
Rita De Gasperi +21 more
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Microstructural Consequences of Blast Lung Injury Characterized with Digital Volume Correlation [PDF]
Frontiers in Materials, 2017 This study focuses on microstructural changes that occur within the mammalian lung when subject to blast and how these changes influence strain distributions within the tissue. Shock tube experiments were performed to generate the blast injured specimens
Hari Arora +12 more
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The Neurovascular Unit as a Locus of Injury in Low-Level Blast-Induced Neurotrauma. [PDF]
Int J Mol SciBlast-induced neurotrauma has received much attention over the past decade. Vascular injury occurs early following blast exposure. Indeed, in animal models that approximate human mild traumatic brain injury or subclinical blast exposure, vascular pathology can occur in the presence of a normal neuropil, suggesting that the vasculature is particularly ...
Elder GA +12 more
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Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain [PDF]
Acta Neuropathologica Communications, 2019 Much concern exists over the role of blast-induced traumatic brain injury (TBI) in the chronic cognitive and mental health problems that develop in veterans and active duty military personnel.
Miguel A. Gama Sosa +18 more
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Repeat low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. [PDF]
PLoS ONE, 2017 Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor ...
Elaine D Por +7 more
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Low-Level Blast Exposure Increases Transient Receptor Potential Vanilloid 1 (TRPV1) Expression in the Rat Cornea. [PDF]
Curr Eye Res, 2016 Blast-related ocular injuries sustained by military personnel have led to rigorous efforts to elucidate the effects of blast exposure on neurosensory function. Recent studies have provided some insight into cognitive and visual deficits sustained following blast exposure; however, limited data are available on the effects of blast on pain and ...
Por ED, Choi JH, Lund BJ.
europepmc +4 more sources
Chronic post-traumatic stress disorder-related traits in a rat model of low-level blast exposure. [PDF]
Behav Brain Res, 2018 The postconcussion syndrome following mild traumatic brain injuries (mTBI) has been regarded as a mostly benign syndrome that typically resolves in the immediate months following injury. However, in some individuals, symptoms become chronic and persistent.
Perez-Garcia G +8 more
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Neurobiology of Disease, 2013 There is strong evidence that primary blast injuries can cause neuropathological alterations in the brain. Clinical findings from war veterans indicating evidence of diffuse axonal injury have been corroborated by numerous primary blast models in animals.
Eugene Park +3 more
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Elevated Axonal Protein Markers Following Repetitive Blast Exposure in Military Personnel
Frontiers in Neuroscience, 2022 Blast exposures that occur during training are common in military personnel; however, the biomarkers that relate to these subtle injuries is not well understood.
Rany Vorn +7 more
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Frontiers in Neurology, 2021 The consequences of blast exposure (including both high-level and low-level blast) have been a focal point of military interest and research for years. Recent mandates from Congress (e.g., National Defense Authorization Act for Fiscal Year 2018, section ...
Jennifer N. Belding +7 more
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