Effects of low-level blast exposure on the nervous system: Is there really a controversy? [PDF]
Frontiers in Neurology, 2014 High-pressure blast waves can cause extensive CNS injury in humans. However, in combat settings such as Iraq and Afghanistan, lower level exposures associated with mild TBI (mTBI) or subclinical exposure have been much more common. Yet controversy exists
Gregory A Elder +2 more
doaj +6 more sources
The effects of repeated low-level blast exposure on hearing in marines
Noise and Health, 2017 Background: The study evaluates a group of Military Service Members specialized in blast explosive training called “Breachers” who are routinely exposed to multiple low-level blasts while teaching breaching at the U.S.
Lina R Kubli +4 more
doaj +5 more sources
Ubiquitin Carboxy-Terminal Hydrolase L1 as a serum neurotrauma biomarker for exposure to occupational low-level blast [PDF]
Frontiers in Neurology, 2015 Repeated exposure to low-level blast is a characteristic of a few select occupations and there is concern that such occupational exposures present risk for traumatic brain injury.
Walter eCarr +7 more
doaj +6 more sources
Low level primary blast injury in rodent brain [PDF]
Frontiers in Neurology, 2011 The incidence of blast attacks and resulting traumatic brain injuries has been on the rise in recent years. Primary blast is one of the mechanisms in which the blast wave can cause injury to the brain. The aim of this study was to investigate the effects
Pamela Boon Li Pun +8 more
doaj +5 more sources
Repeated Low-Level Blast Overpressure Leads to Endovascular Disruption and Alterations in TDP-43 and Piezo2 in a Rat Model of Blast TBI [PDF]
Frontiers in Neurology, 2019 Recent evidence linking repeated low-level blast overpressure exposure in operational and training environments with neurocognitive decline, neuroinflammation, and neurodegenerative processes has prompted concern over the cumulative deleterious effects ...
Lanier Heyburn +12 more
doaj +5 more sources
Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain [PDF]
Acta Neuropathologica Communications, 2019 Much concern exists over the role of blast-induced traumatic brain injury (TBI) in the chronic cognitive and mental health problems that develop in veterans and active duty military personnel.
Miguel A. Gama Sosa +18 more
doaj +3 more sources
Repeat low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. [PDF]
PLoS ONE, 2017 Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor ...
Elaine D Por +7 more
doaj +3 more sources
The Neurovascular Unit as a Locus of Injury in Low-Level Blast-Induced Neurotrauma. [PDF]
Int J Mol SciBlast-induced neurotrauma has received much attention over the past decade. Vascular injury occurs early following blast exposure. Indeed, in animal models that approximate human mild traumatic brain injury or subclinical blast exposure, vascular pathology can occur in the presence of a normal neuropil, suggesting that the vasculature is particularly ...
Elder GA +12 more
europepmc +4 more sources
Late chronic local inflammation, synaptic alterations, vascular remodeling and arteriovenous malformations in the brains of male rats exposed to repetitive low-level blast overpressures [PDF]
Acta Neuropathologica Communications, 2023 In the course of military operations in modern war theaters, blast exposures are associated with the development of a variety of mental health disorders associated with a post-traumatic stress disorder-related features, including anxiety, impulsivity ...
Miguel A. Gama Sosa +18 more
doaj +2 more sources
Transcranial Laser Therapy Does Not Improve Cognitive and Post-Traumatic Stress Disorder?Related Behavioral Traits in Rats Exposed to Repetitive Low-Level Blast Injury [PDF]
Neurotrauma Reports, 2021 Many military veterans who experienced blast-related traumatic brain injuries (TBIs) in the conflicts in Iraq and Afghanistan suffer from chronic cognitive and mental health problems, including post-traumatic stress disorder (PTSD).
Georgina Perez Garcia +12 more
doaj +2 more sources