Results 41 to 50 of about 15,955,258 (264)

Mechanisms and pathophysiology of the low-level blast brain injury in animal models

NeuroImage, 2011
The symptoms of primary blast-induced mTBI, posttraumatic stress disorder and depression overlap. Evidence of an organic basis for these entities has been scarce and controversial. We present a review of animal studies demonstrating that low-level blast causes pathophysiological and functional changes in the brain. We monitor a time period from minutes
Annette, Säljö, Maria, Mayorga, Hayde, Bolouri, Berndt, Svensson, Anders, Hamberger   +4 more
openaire   +2 more sources

Pulmonary Biochemical and Histological Alterations after Repeated Low-Level Blast Overpressure Exposures [PDF]

Toxicological Sciences, 2006
Blast overpressure (BOP), also known as high energy impulse noise, is a damaging outcome of explosive detonations and firing of weapons. Exposure to BOP shock waves alone results in injury predominantly to the hollow organ systems such as auditory, respiratory, and gastrointestinal systems. In recent years, the hazards of BOP that once were confined to
Nabil M, Elsayed, Nikolai V, Gorbunov
openaire   +2 more sources

Lack of chronic neuroinflammation in the absence of focal hemorrhage in a rat model of low-energy blast-induced TBI

Acta Neuropathologica Communications, 2017
Blast-related traumatic brain injury (TBI) has been a common cause of injury in the recent conflicts in Iraq and Afghanistan. Blast waves can damage blood vessels, neurons, and glial cells within the brain.
Miguel A. Gama Sosa, Rita De Gasperi, Georgina S. Perez Garcia, Heidi Sosa, Courtney Searcy, Danielle Vargas, Pierce L. Janssen, Gissel M. Perez, Anna E. Tschiffely, William G. Janssen, Richard M. McCarron, Patrick R. Hof, Fatemeh G. Haghighi, Stephen T. Ahlers, Gregory A. Elder   +14 more
doaj   +1 more source

Genetic sources and loci for wheat head blast resistance identified by genome-wide association analysis

Crop Journal, 2022
The emergence and spread of wheat blast caused by fungal pathogen Magnaporthe oryzae pathotype Triticum is a threat to global wheat production. The resistance level and genetic loci for blast resistance in Chinese germplasm remain unknown. A panel of 266
Lei Wu, Xinyao He, Muhammad Rezaul Kabir, Krishna K. Roy, Md. Babul Anwar, Felix Marza, Yi He, Peng Jiang, Xu Zhang, Pawan K. Singh   +9 more
doaj   +1 more source

Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury

Frontiers in Neurology, 2015
Blast-related traumatic brain injury (TBI) has received much recent attention because of its frequency in the conflicts in Iraq and Afghanistan. This renewed interest has led to a rapid expansion of clinical and animal studies related to blast. In humans,
Gregory A Elder, Miguel A Gama Sosa, Rita eDe Gasperi, James Radford Stone, Dara eDickstein, Fatemeh eHaghighi, Patrick R Hof, Stephen T Ahlers   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

New Jersey's Voluntary Plan for Siting a Low-Level Radioactive Waste Disposal Facility

, 1995
This study outlines New Jersey's plan for disposing of its own low-level radioactive waste. This plan calls for interested communities to volunteer land for a disposal site in their area. This study sets out the steps that an interested community would

core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Experimental and numerical investigations of glass curtain walls subjected to low- level blast loads [PDF]

International Journal of Computational Methods and Experimental Measurements, 2015
A series of three full-scale, nearly-conventional, curtain wall specimens were blast tested in the open arena of the Infrastructure Security and Emergency Responder Research and Training (ISERRT) Facility in Gastonia, NC. The specimens were subjected to low-level blast loads produced from the detonation of high explosives.
Adam D. Ralston, David C. Weggel, Matthew J. Whelan, Hongbing Fang   +3 more
openaire   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source