Results 21 to 30 of about 15,955,258 (264)

Boldine treatment prevents chronic cognitive impairment and exaggerated fear learning in rats exposed to repetitive low-level blast injury [PDF]

Frontiers in Cellular Neuroscience
Many Veterans who experienced blast-related traumatic brain injuries (TBI) during their military service suffer from chronic cognitive and mental health problems including post-traumatic stress disorder (PTSD).
Georgina Perez Garcia, Georgina Perez Garcia, Gissel M. Perez, Rita De Gasperi, Rita De Gasperi, Miguel A. Gama Sosa, Miguel A. Gama Sosa, Serena Yeung, Carolyn W. Zhu, Carolyn W. Zhu, Carolyn W. Zhu, Patrick R. Hof, Patrick R. Hof, Patrick R. Hof, Jiangping Pan, Shahrukh Khalique, Shahrukh Khalique, Alexey Kozlenkov, Alexey Kozlenkov, Wei Zhao, Wei Zhao, Carlos A. Toro, Carlos A. Toro, Carlos A. Toro, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder, Christopher P. Cardozo, Christopher P. Cardozo, Christopher P. Cardozo   +30 more
doaj   +2 more sources

Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure [PDF]

Frontiers in Neurology
IntroductionMany Veterans who experienced blast-related traumatic brain injuries (TBIs) in Iraq and Afghanistan currently suffer from chronic cognitive and mental health problems that include depression and post-traumatic stress disorder (PTSD).
Rita De Gasperi, Rita De Gasperi, Georgina Perez Garcia, Georgina Perez Garcia, Miguel A. Gama Sosa, Miguel A. Gama Sosa, Gissel M. Perez, Rania Abutarboush, Rania Abutarboush, Usmah Kawoos, Usmah Kawoos, Patrick R. Hof, Patrick R. Hof, Patrick R. Hof, Carolyn W. Zhu, Carolyn W. Zhu, Carolyn W. Zhu, Stephen T. Ahlers, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder   +21 more
doaj   +2 more sources

Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation [PDF]

Acta Neuropathologica Communications, 2021
Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is primarily the result of blast wave-induced mechanical disruptions within the neurovascular unit.
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, William G. Janssen, Allison Sowa, Timothy Tetreault, David G. Cook, Susan J. Tappan, Sam Gandy, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder   +17 more
doaj   +2 more sources

Low-level blast exposure disrupts gliovascular and neurovascular connections and induces a chronic vascular pathology in rat brain [PDF]

Acta Neuropathologica Communications, 2019
Much concern exists over the role of blast-induced traumatic brain injury (TBI) in the chronic cognitive and mental health problems that develop in veterans and active duty military personnel.
Miguel A. Gama Sosa, Rita De Gasperi, Georgina S. Perez Garcia, Gissel M. Perez, Courtney Searcy, Danielle Vargas, Alicia Spencer, Pierce L. Janssen, Anna E. Tschiffely, Richard M. McCarron, Benjamin Ache, Rajaram Manoharan, William G. Janssen, Susan J. Tappan, Russell W. Hanson, Sam Gandy, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder   +18 more
doaj   +2 more sources

Repeat low-level blast exposure increases transient receptor potential vanilloid 1 (TRPV1) and endothelin-1 (ET-1) expression in the trigeminal ganglion. [PDF]

PLoS ONE, 2017
Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor ...
Elaine D Por, Melody L Sandoval, Chiquita Thomas-Benson, Teresa A Burke, Allison Doyle Brackley, Nathaniel A Jeske, Jeffery M Cleland, Brian J Lund   +7 more
doaj   +2 more sources

Exposure to a Predator Scent Induces Chronic Behavioral Changes in Rats Previously Exposed to Low-level Blast: Implications for the Relationship of Blast-Related TBI to PTSD. [PDF]

Front Neurol, 2016
Blast-related mild traumatic brain injury (mTBI) has been unfortunately common in veterans who served in the recent conflicts in Iraq and Afghanistan. The postconcussion syndrome associated with these mTBIs has frequently appeared in combination with post-traumatic stress disorder (PTSD). The presence of PTSD has complicated diagnosis, since clinically,
Perez-Garcia G, Gama Sosa MA, De Gasperi R, Lashof-Sullivan M, Maudlin-Jeronimo E, Stone JR, Haghighi F, Ahlers ST, Elder GA.   +8 more
europepmc   +5 more sources

Chronic post-traumatic stress disorder-related traits in a rat model of low-level blast exposure. [PDF]

Behav Brain Res, 2018
The postconcussion syndrome following mild traumatic brain injuries (mTBI) has been regarded as a mostly benign syndrome that typically resolves in the immediate months following injury. However, in some individuals, symptoms become chronic and persistent.
Perez-Garcia G, Gama Sosa MA, De Gasperi R, Lashof-Sullivan M, Maudlin-Jeronimo E, Stone JR, Haghighi F, Ahlers ST, Elder GA.   +8 more
europepmc   +3 more sources

Simulation of the generation and propagation of blast induced shock waves [PDF]

, 2003
Hybrid modelling of blast vibration uses the signal produced from a single hole test shot to simulate the vibration that would be produced by a full-scale production blast.
Yuill, Gavin John
core   +7 more sources

Electrophysiological white matter dysfunction and association with neurobehavioral deficits following low-level primary blast trauma

Neurobiology of Disease, 2013
There is strong evidence that primary blast injuries can cause neuropathological alterations in the brain. Clinical findings from war veterans indicating evidence of diffuse axonal injury have been corroborated by numerous primary blast models in animals.
Eugene Park, Rebecca Eisen, Anna Kinio, Andrew J. Baker   +3 more
doaj   +3 more sources

Elevated Axonal Protein Markers Following Repetitive Blast Exposure in Military Personnel

Frontiers in Neuroscience, 2022
Blast exposures that occur during training are common in military personnel; however, the biomarkers that relate to these subtle injuries is not well understood.
Rany Vorn, Rany Vorn, Rosanne Naunheim, Chen Lai, Chen Lai, Chelsea Wagner, Jessica M. Gill, Jessica M. Gill   +7 more
doaj   +1 more source