Results 21 to 30 of about 215,416 (267)

Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure [PDF]

Frontiers in Neurology
IntroductionMany Veterans who experienced blast-related traumatic brain injuries (TBIs) in Iraq and Afghanistan currently suffer from chronic cognitive and mental health problems that include depression and post-traumatic stress disorder (PTSD).
Rita De Gasperi, Rita De Gasperi, Georgina Perez Garcia, Georgina Perez Garcia, Miguel A. Gama Sosa, Miguel A. Gama Sosa, Gissel M. Perez, Rania Abutarboush, Rania Abutarboush, Usmah Kawoos, Usmah Kawoos, Patrick R. Hof, Patrick R. Hof, Patrick R. Hof, Carolyn W. Zhu, Carolyn W. Zhu, Carolyn W. Zhu, Stephen T. Ahlers, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder, Gregory A. Elder   +21 more
doaj   +2 more sources

Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation [PDF]

Acta Neuropathologica Communications, 2021
Cerebral vascular injury as a consequence of blast-induced traumatic brain injury is primarily the result of blast wave-induced mechanical disruptions within the neurovascular unit.
Miguel A. Gama Sosa, Rita De Gasperi, Dylan Pryor, Georgina S. Perez Garcia, Gissel M. Perez, Rania Abutarboush, Usmah Kawoos, Seth Hogg, Benjamin Ache, William G. Janssen, Allison Sowa, Timothy Tetreault, David G. Cook, Susan J. Tappan, Sam Gandy, Patrick R. Hof, Stephen T. Ahlers, Gregory A. Elder   +17 more
doaj   +2 more sources

Mechanisms and pathophysiology of the low-level blast brain injury in animal models

NeuroImage, 2011
The symptoms of primary blast-induced mTBI, posttraumatic stress disorder and depression overlap. Evidence of an organic basis for these entities has been scarce and controversial. We present a review of animal studies demonstrating that low-level blast causes pathophysiological and functional changes in the brain. We monitor a time period from minutes
Annette, Säljö, Maria, Mayorga, Hayde, Bolouri, Berndt, Svensson, Anders, Hamberger   +4 more
openaire   +3 more sources

Exposure to a Predator Scent Induces Chronic Behavioral Changes in Rats Previously Exposed to Low-level Blast: Implications for the Relationship of Blast-Related TBI to PTSD. [PDF]

Front Neurol, 2016
Blast-related mild traumatic brain injury (mTBI) has been unfortunately common in veterans who served in the recent conflicts in Iraq and Afghanistan. The postconcussion syndrome associated with these mTBIs has frequently appeared in combination with post-traumatic stress disorder (PTSD). The presence of PTSD has complicated diagnosis, since clinically,
Perez-Garcia G, Gama Sosa MA, De Gasperi R, Lashof-Sullivan M, Maudlin-Jeronimo E, Stone JR, Haghighi F, Ahlers ST, Elder GA.   +8 more
europepmc   +6 more sources

Lack of chronic neuroinflammation in the absence of focal hemorrhage in a rat model of low-energy blast-induced TBI

Acta Neuropathologica Communications, 2017
Blast-related traumatic brain injury (TBI) has been a common cause of injury in the recent conflicts in Iraq and Afghanistan. Blast waves can damage blood vessels, neurons, and glial cells within the brain.
Miguel A. Gama Sosa, Rita De Gasperi, Georgina S. Perez Garcia, Heidi Sosa, Courtney Searcy, Danielle Vargas, Pierce L. Janssen, Gissel M. Perez, Anna E. Tschiffely, William G. Janssen, Richard M. McCarron, Patrick R. Hof, Fatemeh G. Haghighi, Stephen T. Ahlers, Gregory A. Elder   +14 more
doaj   +2 more sources

Explosion induced dynamic responses of blast wall on FPSO topside: Blast loading application methods

International Journal of Naval Architecture and Ocean Engineering, 2017
Topside areas on an offshore oil and gas platform are highly susceptible to explosion. A blast wall on these areas plays an important role in preventing explosion damage and must withstand the expected explosion loads.
Ki-Yeob Kang, Kwang-Ho Choi, Jae Woong Choi, Yong Hee Ryu, Jae-Myung Lee   +4 more
doaj   +3 more sources

Electrophysiological white matter dysfunction and association with neurobehavioral deficits following low-level primary blast trauma

Neurobiology of Disease, 2013
There is strong evidence that primary blast injuries can cause neuropathological alterations in the brain. Clinical findings from war veterans indicating evidence of diffuse axonal injury have been corroborated by numerous primary blast models in animals.
Eugene Park, Rebecca Eisen, Anna Kinio, Andrew J. Baker   +3 more
doaj   +3 more sources

Modeling Highly Repetitive Low-level Blast Exposure in Mice. [PDF]

J Vis Exp
Exposure to explosive blasts is a significant risk factor for brain trauma among exposed persons. Although the effects of large blasts on the brain are well understood, the effects of smaller blasts such as those that occur during military training are less understood.
Crabtree A, McEvoy C, Muench P, Ivory RA, Rodriguez J, Omer M, Charles T, Meabon JS.   +7 more
europepmc   +3 more sources

Functional and Structural Neuroimaging Correlates of Repetitive Low-Level Blast Exposure in Career Breachers. [PDF]

J Neurotrauma, 2020
Combat military and civilian law enforcement personnel may be exposed to repetitive low-intensity blast events during training and operations. Persons who use explosives to gain entry (i.e., breach) into buildings are known as “breachers” or dynamic entry personnel. Breachers operate under the guidance of established safety protocols, but despite these
Stone JR, Avants BB, Tustison NJ, Wassermann EM, Gill J, Polejaeva E, Dell KC, Carr W, Yarnell AM, LoPresti ML, Walker P, O'Brien M, Domeisen N, Quick A, Modica CM, Hughes JD, Haran FJ, Goforth C, Ahlers ST.   +18 more
europepmc   +3 more sources

Getting on the Same Page: Consolidating Terminology to Facilitate Cross-Disciplinary Health-Related Blast Research

Frontiers in Neurology, 2021
The consequences of blast exposure (including both high-level and low-level blast) have been a focal point of military interest and research for years. Recent mandates from Congress (e.g., National Defense Authorization Act for Fiscal Year 2018, section ...
Jennifer N. Belding, Jennifer N. Belding, Michael Egnoto, Robyn M. Englert, Robyn M. Englert, Shannon Fitzmaurice, Shannon Fitzmaurice, Cynthia J. Thomsen   +7 more
doaj   +1 more source