Results 51 to 60 of about 202,040 (234)

Experimental and numerical investigations of glass curtain walls subjected to low- level blast loads [PDF]

open access: yesInternational Journal of Computational Methods and Experimental Measurements, 2015
A series of three full-scale, nearly-conventional, curtain wall specimens were blast tested in the open arena of the Infrastructure Security and Emergency Responder Research and Training (ISERRT) Facility in Gastonia, NC. The specimens were subjected to low-level blast loads produced from the detonation of high explosives.
Adam D. Ralston   +3 more
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Comprehensive Review of Experimental Rodent Models of Repeated Blast TBI

open access: yesFrontiers in Neurology, 2019
We reviewed the relevant literature delineating advances in the development of the experimental models of repeated blast TBI (rbTBI). It appears this subject is a relatively unexplored area considering the first work published in 2007 and the bulk of ...
Maciej Skotak   +3 more
doaj   +1 more source

DNA Methylation Patterns of Chronic Explosive Breaching in U.S. Military Warfighters

open access: yesFrontiers in Neurology, 2020
Background: Injuries from exposure to explosions rose dramatically during the Iraq and Afghanistan wars, which motivated investigation of blast-related neurotrauma.
Zhaoyu Wang   +11 more
doaj   +1 more source

Effects of repetitive low-level blast exposure on visual system and ocular structures

open access: yesJournal of Rehabilitation Research and Development, 2015
The purpose of this study was to determine whether repetitive exposure to low-level blasts during military breacher training produces acute and cumulative damage to the ocular tissues or visual system. The effects of low-level blast exposure on high-contrast visual acuity, contrast sensitivity, oculomotor function, color vision, visual field (VF ...
José E, Capó-Aponte   +5 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Explosion induced dynamic responses of blast wall on FPSO topside: Blast loading application methods

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2017
Topside areas on an offshore oil and gas platform are highly susceptible to explosion. A blast wall on these areas plays an important role in preventing explosion damage and must withstand the expected explosion loads.
Ki-Yeob Kang   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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