Results 211 to 220 of about 188,098 (288)

Identification of Coagulation Phenotypes Using Viscoelastic and Conventional Assays During Veno‐Venous Extracorporeal Membrane Oxygenation: A Hierarchical Clustering Analysis

Artificial Organs, EarlyView.
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada, Yudai Iwasaki, Yusuke Takei, Moe Oyama, Ami Tanaka, Shinichi Yamaguchi, Naoya Kobayashi, Daisuke Konno, Takuya Shiga, Masanori Yamauchi   +9 more
wiley   +1 more source

Early Treatment With Curative Dose Low-Molecular-Weight Heparin (LMWH) Versus Plasmapheresis in Severe Acute Pancreatitis in Intensive Care: A Comparative Study. [PDF]

Cureus
Yacine A, Mourad O, Soheib Z, Salem H.
europepmc   +1 more source

Anticoagulation Strategies in Adults Undergoing Extracorporeal Membrane Oxygenation: A Systematic Review and Meta‐Analysis

Artificial Organs, EarlyView.
In this meta‐analysis of 2 775 adult ECMO patients from non‐randomized studies, direct thrombin inhibitors and low‐molecular‐weight heparins demonstrated a favorable efficacy and safety profile over unfractionated heparin. These findings suggest them to be effective alternatives to unfractionated heparin, underscoring the urgent need for randomized ...
Vincenz Scharner, Karoline Lenz, Harald Herkner, Nina Buchtele, Thomas Staudinger, Eva Schaden, Marion Wiegele, Johannes Gratz   +7 more
wiley   +1 more source

Efficacy and safety of tranexamic acid combined with low molecular weight heparin versus fondaparinux sodium following total knee arthroplasty: a retrospective cohort study. [PDF]

Front Pharmacol
Haibier A, Pan M, Anwar D, Ma P.
europepmc   +1 more source

International Delphi consensus on feminising genital surgery in assigned‐male‐at‐birth individuals

BJU International, EarlyView.
Objective To achieve an international expert consensus among surgeons on the indications, contraindications, and perioperative management of feminising genital surgery (FGS) for assigned‐male‐at‐birth (AMAB) individuals, using a Delphi process. Methods A two‐round on‐line Delphi survey (May–July 2025) followed by a final consensus meeting (September ...
Marta Pezzoli, Mattia Lo Re, Valeria Pizziconi, Marco Falcone, Mirko Preto, Marco Capece, Michele Rizzo, Guglielmo Mantica, Francesco Chierigo, Malte Vetterlein, Patrizio Vicini, François‐Xavier Madec, Paul Neuville, Wai Gin (Don) Lee, Francesca Vedovo, Saskia Morgenstern, Marjan Waterloos, Miroslav Djordjevic, Wesley Verla, Lukasz Bialek, Juan Diego Tinajero, Jordán Scherñuk, Tim Ludwig, Silke Riechardt, Lisa Szyper, Maren Wenk, Jochen Heß, Julia Bohr, Andrea Minervini, Andrea Cocci, on behalf of the Italian Society of Urodynamics (SIUD)   +30 more
wiley   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Effect of Aspirin Versus Low-Molecular-Weight Heparin for Thromboprophylaxis in High-Risk and Fracture Location Subpopulations: A Secondary Analysis of the PREVENT CLOT Trial. [PDF]

J Orthop Trauma
Tarpada SP, O'Hara NN, Stein DM, DeSantis AJ, Castillo RC, Frey KP, Slobogean GP, Gitajn IL, Gaski GE, Kempton LB, Kleweno CP, Firoozabadi R, Cuschieri J, Christmas AB, Claridge JA, Marvel D, O'Toole RV, METRC.   +17 more
europepmc   +1 more source

Direct oral anticoagulants versus low-molecular-weight heparin for thromboprophylaxis in cancer-related surgeries: A meta-analysis of efficacy and safety outcomes. [PDF]

Am Heart J Plus
Mousavi A, Shojaei S, Dastjerdi P, Rahmati S, Izadpanahi K, Pishraft-Sabet H, Afshar EJ, Salehi K, Sabri M, Arbatan MN, Fallahtafti P, Wilbert A, Ambrosy AP, Syed MA, Iskander M, Hosseini K.   +15 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Efficacy and safety of low-molecular-weight heparin or rivaroxaban combined with immunotherapy and chemotherapy in the treatment of advanced nonsmall cell lung cancer: a prospective, randomized, controlled clinical study. [PDF]

Cancer Immunol Immunother
Zhang H, Li J, Yuan G, Huang S, Li X.
europepmc   +1 more source