Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
The Role of Extended Thromboprophylaxis With Low-Molecular-Weight Heparin Following Abdominopelvic Surgery for Cancer. [PDF]
Adeoye L, Bannerman-Martin A.
europepmc +1 more source
Automodification of N‐terminal serine residues facilitates PARP2 release from DNA
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar +6 more
wiley +1 more source
Significance of 80-S ribosomes associated with Neurospora crassa mitochondria [PDF]
Bücher, Theodor +8 more
core
Analysis of the Application Value of Low Molecular Weight Heparin Combined with Heparin in Patients with Chorionic Bump in Early Pregnancy. [PDF]
Peng XT, Cai ZH, Shen J, Zhu HY.
europepmc +1 more source
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito +8 more
wiley +1 more source
Efficacy and safety study of tranexamic acid combined with low-molecular-weight heparin and nadroparin calcium in postoperative application after joint replacement: a retrospective cohort study. [PDF]
Haibier A +3 more
europepmc +1 more source
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
Optimal Management of Bleeding and Thrombosis in Total Knee Arthroplasty: Tranexamic Acid With Acetylsalicylic Acid or Low-Molecular-Weight Heparin. [PDF]
Uzunay Z +3 more
europepmc +1 more source
Evaluating the efficacy of low-molecular-weight heparin in managing umbilical artery thrombosis during pregnancy: does it offer therapeutic benefits? [PDF]
Zhao P +5 more
europepmc +1 more source

