Results 221 to 230 of about 12,776,407 (326)

The Histidine 382 Residue Influences the Thermal Stability and Binding Propensity of the E2 Domain of Amyloid Precursor Protein

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu, Candice Ngubane, Zamaxasibe Nxele, Raymond Hewer, Alexandré Delport   +4 more
wiley   +1 more source

Multifunctional applications and research advances of low-molecular-weight heparin. [PDF]

Front Pharmacol
Zhang Y, Guo S, Xu J.
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Extended thromboprophylaxis after hip fracture surgery: Real-world evidence of direct oral anticoagulants versus low molecular weight heparin of unfractionated heparin. [PDF]

PLoS One
Clavijo MM, Ruiz JI, Brindicci MR, Rodriguez P, Wauters V, Reparaz MLAV, Mountford A, Monteagudo M, Camarero M, Casali CE, Mahuad C, Aizpurua F, Zerga ME, Ventura A, Siciliano N, Garate G.   +15 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Urticarial reaction to low molecular weight heparin injections. [PDF]

Obstet Med
Hill A, Williams C, Finucane K, Carson N, Neuberger F, Xie F.   +5 more
europepmc   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Efficacy and safety of rivaroxaban versus low-molecular-weight heparin for the prevention of symptomatic in-hospital venous thrombosis following primary total hip and knee arthroplasty: a large-sample, multicenter, retrospective study. [PDF]

BMC Musculoskelet Disord
Liao Y, Deng J, Shi X, Wang X, Tan H, Cao G.   +5 more
europepmc   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

Low-Molecular-Weight Heparin Plus Insulin in Hypertriglyceridemic Acute Pancreatitis: A Randomized Clinical Trial.

JAMA Netw Open
He W, Ding L, Liu Z, Hua M, Zhou Y, Gong M, Sheng J, Wu X, Fan H, Shu H, Wang R, Xun L, Huang C, Guo F, Cao C, Zhan Z, Chen H, Qian X, Liu Q, Li Q, Tang Z, Xiong Y, Xie P, Yu B, Wan J, Ke H, Wu Y, Hu Y, Ai J, Huang X, Lei Y, Xiong H, Liu Z, Zhu Y, Luo L, Xia L, Ke L, Cai W, Huang W, Li W, Windsor J, Sutton R, Lv N, Zhu Y, Chinese Acute Pancreatitis Clinical Trials Group (CAPCTG).   +44 more
europepmc   +1 more source