Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor [PDF]
Background: Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature. This drug-induced action tremor has been proposed as a model of
Handforth, Adrian
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Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome [PDF]
Gamma-hydroxybutyrate (GHB) is a short chain fatty acid endogenously produced within the central nervous system (CNS) and acts as a precursor and metabolite of the inhibitory neurotransmitter γ-aminobutyric acid (GABA).
BUSARDO', FRANCESCO PAOLO +4 more
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Correlation of changes in patient-reported quality of life with physician-rated global impression of change in patients with narcolepsy participating in a clinical trial of sodium oxybate : a post hoc analysis [PDF]
Introduction: Narcolepsy patients report lower health-related quality of life (HRQoL) than the general population, as measured by the Short Form-36 Health Survey (SF-36).
Black, Jed +7 more
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Narcolepsy is mainly associated with excessive daytime sleepiness, but the characteristic feature is abnormal rapid eye movement (REM) sleep phenomena.
Dauvilliers, Yves +2 more
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Narcolepsy :a review amongst sleep disorders. [PDF]
Narcolepsy is a sleep disorder known and studied about from time to time is a sleep disorder characterized by a combination of myriad of symptoms including excessive day time sleepiness with recurrent irresistible sleep attacks , hypnogogic ...
Ahmed, Omer +2 more
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Do capillary dried blood spot concentrations of gamma-hydroxybutyric acid mirror those in venous blood? : a comparative study [PDF]
Abanades +19 more
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Functional ADA Polymorphism Increases Sleep Depth and Reduces Vigilant Attention in Humans [PDF]
Homeostatically regulated slow-wave oscillations in non-rapid eye movement (REM) sleep may reflect synaptic changes across the sleep-wake continuum and the restorative function of sleep.
Bachmann, Valérie +7 more
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Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons [PDF]
A Guidotti +54 more
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Behavioral Sleep Medicine Services for Hypersomnia Disorders: A Survey Study [PDF]
Megan Crawford
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