Results 71 to 80 of about 8,676,773 (167)

Criteria for Gauging Response to Sodium Oxybate for Narcolepsy

, 2018
Our objective was to define responder criteria using an anchor-based approach for frequency of cataplexy attacks and excessive daytime sleepiness in narcolepsy patients undergoing sodium oxybate treatment. We used pooled data from two randomized, placebo-
Terri E. Weaver (7931498), Alana D. Steffen (7931495), Chinglin Lai (5169872)   +2 more
core  

Differential effects of sodium oxybate and baclofen on EEG, sleep, neurobehavioral performance, and memory

, 2012
Sodium oxybate (SO) is a GABAβ agonist used to treat the sleep disorder narcolepsy. SO was shown to increase slow wave sleep (SWS) and EEG delta power (0.75-4.5 Hz), both indexes of NREM sleep (NREMS) intensity and depth, suggesting that SO enhances ...
Schwartz, S., Lecciso, G., Constantinescu, Irina Oana, Vienne, Julie, Franken, P., Constantinescu, I., Vienne, J., Tafti, M., Heinzer, Raphael, Franken, Paul, Schwartz, Sophie, Heinzer, R., Lecciso, Gianpaolo, Tafti, Mehdi   +13 more
core   +1 more source

Pharmacokinetics and formulation selection of FT218, an investigational controlledrelease sodium oxybate formulation designed for once nightly dosing

, 2019
Introduction: Sodium oxybate is indicated for the treatment of Excessive Daytime Sleepiness (EDS) and cataplexy in patients with narcolepsy. The currently marketed product, an immediate release (IR) sodium oxybate is required to be taken twice nightly ...
Monteith, D, Roth, Thomas, Grassot, J, Castellan, C   +3 more
core   +1 more source

Treatment with Sodium Oxybate in Children and Young Adults – a Register Study in Halland and Västra Götaland

, 2016
Background: Narcolepsy is a chronical neurological disease with a prevalence of 0,02-0,05 % in the western world. A massive increase in incidence occurred after the vaccination with Pandemrix against the H1N1-influenza.
Björck, Per
core  

Experiences of people with narcolepsy who switched from sodium oxybate to low-sodium oxybate: a plain language summary

Future Neurology
Aatif M. Husain, Phyllis C. Zee, Eileen B. Leary, Douglas S. Fuller, Shawn Candler, Marisa Whalen, Monica Gow, Charles J. Bae   +7 more
openaire   +1 more source

Compatibility studies of Sodium oxybate oral solution

, 2019
Nātrija oksibutirāta orālā šķīduma savietojamības pētījumi. Valtere L. K., darba vadītāji Dr. ķīm., prof. Vīksna A., Mg. ķīm. Kuprevičs K., bakalaura darbs, 68 lappuses, 33 literatūras avoti, 4 pielikumi. Latviešu valodā. Darbā tika veikti savietojamības
Valtere, Līva Klinta
core  

Response to Letter to the Editor Regarding “Implications of Oxybate Dosing Regimen for Sleep, Sleep Architecture, and Disrupted Nighttime Sleep in Patients With Narcolepsy: A Commentary”

Neurology and Therapy
Chad Ruoff, Shawn Candler, Jed Black
doaj   +1 more source

Optimizing patient outcomes and empowering the patient-clinician partnership. [PDF]

Sleep Adv
Thorpy M.
europepmc   +1 more source

Introduction: sodium oxybate and cardiovascular safety: reconciling 20 years of clinical and research experience with sodium intake guidelines. [PDF]

Sleep Adv
Kushida CA.
europepmc   +1 more source

Sodium-Containing Pharmaceutical Products as Contributors to Cardiovascular Risk. [PDF]

J Am Heart Assoc
White WB, Kovacs RJ.
europepmc   +1 more source