Results 31 to 40 of about 123,721 (262)
The new fatigue data sheet, No. 133, discloses low- and high-cycle fatigue properties of A2017-T4 aluminium alloys. Two types of low-cycle fatigue tests were conducted under strain-controlled conditions.
Yoshiyuki Furuya +4 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Assessment of Durability of the Toothed Segment Based on FEM Analysis and Low Fatigue Cycle Test
The development of a novel design for the toothed segment of drive transmission in longwall shearer is expected to significantly reduce the cost of individual components of the feed system and the related work of repair and renovations, increasing at the
Piekło J., Maj M., Żuczek R., Pysz S.
doaj +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Identification of low cycle fatigue parameters
The article describes a new approach to the processing of experimental data coming from low-cycle fatigue (LCF) tests. The data may be either tables from the standard tests, or a time series of loading processes and corresponding numbers of cycles to ...
Balda M.
doaj
Cumulative Damage in Very High/Low Cycle Combined Fatigue for TC21 Titanium Alloy
The effect of low cycle fatigue (LCF) predamage with no precracks on very high cycle fatigue (VHCF) properties, and crack initiation characteristics for TC21 titanium alloy, was investigated.
Baohua Nie +7 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Study on high-low cycle fretting fatigue life of Inconel718 tenon structure
The turbine blades of aero-engines are subjected to cyclic high-low cycle loads in actual service environments,which is a typical high-low cycle micro motion fatigue condition. The frequent occurrence of fatigue fracture in turbine blades due to fretting
YANG Xiaolin +3 more
doaj +1 more source
In the present article, the low-cycle fatigue lifetime of carbon/epoxy laminated composites has been investigated. The sensitivity analysis has been also performed to study effects of the displacement amplitude and the loading frequency on the low-cycle ...
Azadi Mohammad +2 more
doaj +1 more source
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source

