Results 1 to 10 of about 579,543 (207)
Inclisiran, Low-Density Lipoprotein Cholesterol and Lipoprotein (a)
Pharmaceuticals, 2023 Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e.,
Niki Katsiki +3 more
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Low-Density Lipoprotein and High-Density Lipoprotein as Biomarkers for Inflammatory Bowel Disease Activity Assessment [PDF]
International Journal of General MedicineXi Zhao,1,* Wei Yan,2,* Li Wang,3,* Qinyu Feng,1 Yingzhi Pang,2 Yanping Wang,1 Meihui Tao,1 Jingyue Zhang,1 Yu Fu1 1Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and ...
Zhao X +8 more
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Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease
Cells, 2023 Alterations in lipid composition and disturbed lipoprotein metabolism are involved in the pathomechanism of Huntington’s disease (HD). Here, we measured 112 lipoprotein subfractions and components in the plasma of 20 normal controls, 24 symptomatic ...
Kuo-Hsuan Chang +5 more
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Biomedicines, 2022 Background: Mechanisms by which chronic kidney disease (CKD) influences fibrin clot properties in atrial fibrillation (AF) remain ill-defined. We aimed to investigate the effects of AF and CKD on fibrin clot properties and lipoproteins, and determine the
Wern Yew Ding +3 more
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Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9
Journal of Lipid Research, 2008 Proprotein convertase subtilisin/kexin type 9 (PCSK9) has gained attention as a key regulator of serum low density lipoprotein cholesterol (LDL-C) levels. This novel protease causes the degradation of hepatic low density lipoprotein receptors. In humans,
Holly E. Careskey +5 more
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Oxidized Low-Density Lipoprotein [PDF]
, 2009 Oxidized low-density lipoprotein (Ox-LDL) has been studied for over 25 years. Numerous pro- and anti-atherogenic properties have been attributed to Ox-LDL. Yet, Ox-LDL has neither been defined nor characterized, as its components and composition change depending on its source, method of preparation, storage, and use. It contains unoxidized and oxidized
Sampath, Parthasarathy +3 more
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The effect of eight weeks of 30-20-10 interval training on serum spexin levels and lipid profile in obese middle-aged men [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2023 Background and Purpose: The purpose of this study was to investigate the effect of 30-20-10 interval training on the serum spexin level and lipid profile of obese men in order to measure the effect of physical activity on increasing spexin and improving ...
Hamid Yazdanshenas +2 more
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Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?
Journal of Lipid Research, 1985 The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry +3 more
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High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]
Journal of Lipid Research, 2014 The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger +6 more
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Journal of Lipid Research, 2014 Hyperlipidemia and arterial cholesterol accumulation are primary causes of cardiovascular events. Monogenic forms of hyperlipidemia and recent genome-wide association studies indicate that genetics plays an important role.
Elizabeth A. O'Hare +5 more
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