Results 1 to 10 of about 605,029 (256)

Emerging low-density lipoprotein therapies: Targeting PCSK9 for low-density lipoprotein reduction [PDF]

Journal of Clinical Lipidology, 2013
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protein secreted by the hepatocyte that regulates the surface expression of low-density lipoprotein (LDL) receptors by targeting them for lysosomal degradation. Statins enhance PCSK9 synthesis, an effect that blunts the LDL-cholesterol (-C)-lowering effectiveness of statins.
Michael H. Davidson
openalex   +3 more sources

Childhood Obesity and Familial Hypercholesterolemia: Genetic Diseases that Contribute to Cardiovascular Disease [PDF]

, 2014
Childhood obesity occurs as the result of an imbalance between caloric intake and energy expenditure. Genetic risk factors for obesity have become an area of research due to its permanency.
Caudle, Alyssa
core   +1 more source

Thematic review series: Patient-Oriented Research. What we have learned about VLDL and LDL metabolism from human kinetics studies

Journal of Lipid Research, 2006
Lipoprotein metabolism is the result of a complex network of many individual components. Abnormal lipoprotein concentrations can result from changes in the production, conversion, or catabolism of lipoprotein particles. Studies in hypolipoproteinemia and
Klaus G. Parhofer, P. Hugh R. Barrett
doaj   +1 more source

Study of agreement between LDL size as measured by nuclear magnetic resonance and gradient gel electrophoresis

Journal of Lipid Research, 2004
LDL particle size can be measured by gradient gel electrophoresis (GGE) and NMR. The agreement between the two methods has not been extensively evaluated. Therefore, we measured LDL size by NMR and GGE in 324 individuals (152 with type 1 diabetes and 172
D.R. Witte, M.R. Taskinen, H. Perttunen-Nio, A. van Tol, S. Livingstone, H.M. Colhoun   +5 more
doaj   +1 more source

The effects of non-nutritive sweeteners on lipid profile in adults: a systematic review and meta-analysis of randomized controlled clinical trials

Scientific Reports
Non-nutritive sweeteners (NNS) have been suggested as a viable solution to reduce sugar consumption. However, conflicting and uncertain evidence regarding their impact on lipid profile exists. This meta-analysis assesses the effects of different types of
AmirHossein Najafi, Fatemeh Moghtaderi, Behnaz Seyedjafari, Kimia Rostampour, Amin Salehi-Abargouei   +4 more
doaj   +1 more source

Oscillating shear index, wall shear stress and low density lipoprotein accumulation in human RCAs [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Fytanidis, DK, Giannoglou, GD, Papaioannou, VC, Soulis, JV   +4 more
core  

Gambaran Kadar Apolipoprotein B (APO-B) Serum Pada Vegetarian Lacto-ovo [PDF]

, 2017
: Lacto-ovo vegetarian is the most common type of vegetarians in society. This type of vegetarian does not consume fish and meats, except eggs, milk, and its products. Apolipoprotein is a protein component of lipoprotein.
Assa, Y. A. (Youla), Kaligis, S. H. (Stefana), Setiawan, H. G. (Hengky)   +2 more
core  

Evaluating the Association Between Low-Density Lipoprotein Cholesterol Reduction and Relative and Absolute Effects of Statin Treatment

, 2022
Paula Byrne, Maryanne Demasi, Mark Jones, Susan M. Smith, Kirsty O’Brien, Robert DuBroff   +5 more
openalex   +2 more sources

Metabolic effects of berberine on liver phosphatidate phosphohydrolase in rats fed on high lipogenic diet: An additional mechanism for the hypolipidemic effects of berberine [PDF]

, 2014
Objective: To evaluate the effects of berberine (BBR) on the liver phosphatidate phosphohydrolase (PAP) and plasma lipids in rats fed on high lipogenic and normal diet. Methods: Forty rats were randomly divided into 5 groups.
Bakhshesh, M., Heidarian, E., Khoshdel, A., Rafieian-Kopaei, M.   +3 more
core  

Comparison of ten formulae for calculating low-density lipoprotein cholesterol with direct low-density lipoprotein cholesterol measurement

Current Medicine Research and Practice
Background Accurate lipid profile assessment, mainly low-density lipoprotein cholesterol (LDL-C) measurement, is crucial for diagnosing and managing cardiovascular disease (CVD).
Suriyan S. Nair, Reshma Kiran, K. K. Jisna, M. B. Prathima, P Sushith, Janice D’sa   +5 more
doaj   +1 more source