Results 11 to 20 of about 11,362,691 (296)

Oscillating shear index, wall shear stress and low density lipoprotein accumulation in human RCAs [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Soulis, JV, Giannoglou, GD, Fytanidis, DK, Papaioannou, VC, 3rd Micro and Nano Flows Conference (MNF2011)   +4 more
core   +6 more sources

Wall shear stress and low density lipoprotein concentration in stented arteries [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Soulis, JV, Giannoglou, GD, Karagkiozaki, VC, Fytanidis, DK, Seralidou, KV, 3rd Micro and Nano Flows Conference (MNF2011)   +5 more
core   +6 more sources

Mathematical model for low density lipoprotein (LDL) endocytosis by hepatocytes [PDF]

, 2008
Individuals with elevated levels of plasma low density lipoprotein (LDL) cholesterol (LDL-C) are considered to be at risk of developing coronary heart disease.
B. O’Malley, J. A. D. Wattis, H. Blackburn, Wattis, JA, H. M. Byrne, L. Pickersgill, O'Malley, B, Panovska, J, Pickersgill, L, Blackburn, H, Byrne, HM, Byrne, Helen, K. G. Jackson, Wattis, JAD, Jackson, KG, J. Panovska, Panovska, J., O'Malley, B., Pickersgill, L., Wattis, J.A.D., Jackson, K.G., Blackburn, H., Byrne, H.M.   +22 more
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PCSK9 Inhibition: From Current Advances to Evolving Future

Cells, 2022
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secretory serine protease synthesized primarily by the liver. It mainly promotes the degradation of low-density lipoprotein receptor (LDL-R) by binding LDL-R, reducing low-density lipoprotein ...
Chunping Liu, Jing Chen, Huiqi Chen, Tong Zhang, Dongyue He, Qiyuan Luo, Jiaxin Chi, Zebin Hong, Yizhong Liao, Shihui Zhang, Qizhe Wu, Huan Cen, Guangzhong Chen, Jinxin Li, Lei Wang   +14 more
doaj   +1 more source

The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis[S]

Journal of Lipid Research, 2015
Perlecan is a major heparan sulfate (HS) proteoglycan in the arterial wall. Previous studies have linked it to atherosclerosis. Perlecan contains a core protein and three HS side chains. Its core protein has five domains (DI–DV) with disparate structures
Yu-Xin Xu, David Ashline, Li Liu, Carlos Tassa, Stanley Y. Shaw, Katya Ravid, Matthew D. Layne, Vernon Reinhold, Phillips W. Robbins   +8 more
doaj   +1 more source

Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein [PDF]

, 2006
Oxidation of low-density lipoprotein (LDL) generates pro-inflammatory and pro-thrombotic mediators that play a crucial role in cardiovascular and inflammatory diseases.
Wolfgang Siess, Siess, Wolfgang
core   +1 more source

Uptake of synthetic low density lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategy [PDF]

, 2010
Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis.
Jørgensen, Heather G., Jorgensen, Heather G., Tessa L. Holyoake, Heather G. Jørgensen, Scobie, Linda; id_orcid, Elliott, Moira A., Scobie, Linda, Crossan, Claire, Hatziieremia, Sophia, Zhou, Peixun; id_orcid, Elliott, Moira A, Sophia Hatziieremia, Michie, Alison M, Holyoake, Tessa L., Holyoake, Tessa L, Jørgensen, Heather G, Alison M. Michie, Halbert, Gavin W., Linda Scobie, Gavin W. Halbert, Moira A. Elliott, Claire Crossan, Michie, Alison M., Peixun Zhou, Halbert, Gavin W, Zhou, Peixun   +25 more
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Impaired receptor-mediated catabolism of low density lipoproteins in fasted rabbits.

Journal of Lipid Research, 1984
Plasma cholesterol levels of New Zealand white rabbits, fasted for 9 days, increased 4-fold owing to elevated levels of low density lipoproteins and intermediate density lipoproteins.
J B Stoudemire, G Renaud, D M Shames, R J Havel   +3 more
doaj   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang, Weber, Christian, Kim S. C. Weber, Weber, Kim S.C., Weber, Peter C., Wolfgang Erl, Peter C. Weber, Christian Weber   +7 more
core   +1 more source

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

Journal of Lipid Research, 2005
Apolipoprotein E (apoE) associates with lipoproteins and mediates their interaction with members of the LDL receptor family. ApoE exists as three common isoforms that have important distinct functional and biological properties.
Jose Ruiz, Diana Kouiavskaia, Molly Migliorini, Susan Robinson, Evgueni L. Saenko, Natalia Gorlatova, Donghua Li, Daniel Lawrence, Bradley T. Hyman, Karl H. Weisgraber, Dudley K. Strickland   +10 more
doaj   +1 more source