Results 111 to 120 of about 11,210,903 (298)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Gravitoastronomy with neutron stars [PDF]
, 2004 Recent advances in gravitational wave detectors mean that we can start to make astrophysically important statements about the physics of neutron stars based on observed upper limits to their gravitational luminosity.
Woan, G., Graham Woan
core +1 more source
Variations in the Milky Way’s Stellar Mass Function at [Fe/H] < −1
The Astrophysical Journal LettersWe present the first determination of the Galactic stellar mass function (MF) for low-mass stars (0.2–0.5 M _⊙ ) at metallicities [Fe/H] ≲ −1. A sample of ∼53,000 stars was selected as metal-poor on the basis of both their halolike orbits and their ...
Jiadong Li +16 more
doaj +1 more source
The birthline for low-mass stars
The Astrophysical Journal, 1983 Using the results of protostar theory, the locus in the Hertzsprung-Russell diagram is found where pre-main-sequence stars of subsolar mass should begin their quasi-static contraction phase and first appear as visible objects. This 'birthline' is in striking agreement with observations of T Tauri stars, providing a strong confirmation of the fact that ...
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Astronomy & AstrophysicsContext. The F-, G-, K-, and M-type stars are the most abundant stellar population in the Milky Way and are expected to contribute to its diffuse X-ray emission.
Zheng Xueying +17 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Final Evolution of a Low-Mass Star. I
The Astrophysical Journal, 1970 Low mass star evolution from helium burning to white dwarf, describing red giant and mass loss stages in ...
William K. Rose, Richard L. Smith
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Mass observation / by Mass Observation.
, 1945 Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core