Results 141 to 150 of about 13,442,946 (252)

Observations of Extremely Metal-poor O Stars: Weak Winds and Constraints for Evolution Models

The Astrophysical Journal
Metal-poor massive stars drive the evolution of low-mass galaxies, both locally and at high redshift. However, quantifying the feedback they impart to their local surroundings remains uncertain because models of stellar evolution, mass loss, and ionizing
O. Grace Telford, John Chisholm, Andreas A. C. Sander, Varsha Ramachandran, Kristen B. W. McQuinn, Danielle A. Berg   +5 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Euclid: Quick Data Release (Q1) – Ultracool dwarfs in the Euclid Deep Fields★

Astronomy & Astrophysics
Ultracool dwarfs (UCDs) encompass the lowest-mass stars and brown dwarfs at the stellar–substellar boundary. These intrinsically faint objects are challenging to detect.
Mohandasan A., Smart R. L., Reylé C., Le Brun V., Pérez-Garrido A., Bañados E., Jones H. R. A., Dupuy T., Goldman B., Casewell S. L., Zapatero Osorio M. R., Rejkuba M., Martín E. L., Muñoz Torres S., Domínguez-Tagle C., Žerjal M., Huélamo N., Lodieu N., Cruz P., Majidi F. Z., Rebolo R., Phillips M. W., Zhang J.-Y., Aghanim N., Altieri B., Amara A., Andreon S., Auricchio N., Baccigalupi C., Baldi M., Balestra A., Bardelli S., Battaglia P., Biviano A., Bonchi A., Branchini E., Brescia M., Brinchmann J., Camera S., Cañas-Herrera G., Capobianco V., Carbone C., Carretero J., Casas S., Castellano M., Castignani G., Cavuoti S., Chambers K. C., Cimatti A., Colodro-Conde C., Congedo G., Conselice C. J., Conversi L., Copin Y., Costille A., Courbin F., Courtois H. M., Cropper M., Da Silva A., Degaudenzi H., De Lucia G., Dole H., Douspis M., Dubath F., Dupac X., Dusini S., Escoffier S., Farina M., Faustini F., Ferriol S., Fotopoulou S., Frailis M., Franceschi E., Galeotta S., George K., Gillard W., Gillis B., Giocoli C., Gracia-Carpio J., Granett B. R., Grazian A., Grupp F., Haugan S. V. H., Hoar J., Holmes W., Hook I. M., Hormuth F., Hornstrup A., Jahnke K., Jhabvala M., Keihänen E., Kermiche S., Kiessling A., Kubik B., Kuijken K., Kümmel M., Kunz M., Kurki-Suonio H., Le Boulc’h Q., Le Brun A. M. C., Le Mignant D., Ligori S., Lilje P. B., Lindholm V., Lloro I., Mainetti G., Maino D., Maiorano E., Mansutti O., Marcin S., Marggraf O., Martinelli M., Martinet N., Marulli F., Massey R., Medinaceli E., Mei S., Mellier Y., Meneghetti M., Merlin E., Meylan G., Mora A., Moresco M., Moscardini L., Nakajima R., Neissner C., Niemi S.-M., Padilla C., Paltani S., Pasian F., Pedersen K., Percival W. J., Pettorino V., Pires S., Polenta G., Poncet M., Popa L. A., Pozzetti L., Raison F., Renzi A., Rhodes J., Riccio G., Romelli E., Roncarelli M., Saglia R., Sakr Z., Sapone D., Sartoris B., Schewtschenko J. A., Schirmer M., Schneider P., Schrabback T., Secroun A., Seidel G., Serrano S., Simon P., Sirignano C., Sirri G., Stanco L., Steinwagner J., Surace C., Tallada-Crespí P., Taylor A. N., Tereno I., Toledo-Moreo R., Torradeflot F., Tsyganov A., Tutusaus I., Valenziano L., Valiviita J., Vassallo T., Kleijn G. Verdoes, Veropalumbo A., Vibert D., Wang Y., Weller J., Zacchei A., Zamorani G., Zerbi F. M., Zucca E., Martín-Fleitas J., Scottez V.   +181 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Digging into the Interior of Hot Cores with ALMA (DIHCA). VI. The Formation of Low-mass Multiple Systems in High-mass Cluster-forming Regions

The Astrophysical Journal
Most stars form in multiple systems, with profound implications in numerous astronomical phenomena intrinsically linked to multiplicity. However, our knowledge about the process of how multiple stellar systems form is incomplete and biased toward nearby ...
Qiu-yi Luo, Patricio Sanhueza, Stella S. R. Offner, Fernando Olguin, Adam Ginsburg, Fumitaka Nakamura, Kaho Morii, Yu Cheng, Kei E. I. Tanaka, Junhao Liu, Tie Liu, Xing Lu, Qizhou Zhang, Kotomi Taniguchi, Piyali Saha, Shanghuo Li, Xiaofeng Mai   +16 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Equilibria and oscillations of magnetised neutron stars

, 2010
We investigate equilibrium configurations and oscillation spectra of neutron stars,modelled as rotating magnetised fluid bodies in Newtonian gravity. We also explorethe idea that these model neutron stars could have dynamics analogous to rigid-bodyfree ...
Lander, Samuel Kenneth
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Realistic Uncertainties for Fundamental Properties of Asteroseismic Red Giants and the Interplay between Mixing Length, Metallicity, and

The Astrophysical Journal
Asteroseismic modeling is a powerful way to derive stellar properties. However, the derived quantities are limited by built-in assumptions used in stellar models.
Yaguang Li, Timothy R. Bedding, Daniel Huber, Dennis Stello, Jennifer van Saders, Yixiao Zhou, Courtney L. Crawford, Meridith Joyce, Tanda Li, Simon J. Murphy, K. R. Sreenivas   +10 more
doaj   +1 more source