Results 141 to 150 of about 11,210,903 (298)

Magnetic Doppler imaging of early-type stars

, 2010
Doppler imaging of early-type magnetic stars is the most advanced method to interpret their line profile variations. DI allows us to study directly a complex interplay between chemical spots, magnetic fields, and the mass loss.
Iosif Romanyuk, Kochukhov, Oleg,, Mary E. Oksala, Romanyuk, Iosif, Thomas Rivinius, Rivinius, Thomas, Oksala, Mary E., Oleg Kochukhov   +7 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Chemical Abundances in the Metal-Poor Globular Cluster ESO 280-SC06: A Formerly Massive, Tidally Disrupted Globular Cluster

The Open Journal of Astrophysics
We present the first high-resolution abundance study of ESO 280-SC06, one of the least luminous and most metal-poor gravitationally bound Milky Way globular clusters.
Sam A Usman, Alexander P. Ji, Jandrie Rodriguez, Jeffrey D. Simpson, Sarah L. Martell, Ting S. Li, Ana Bonaca, Shivani Shah, Madeleine McKenzie   +8 more
doaj   +1 more source

The rotation of low mass stars at 30 Myr in the cluster NGC 3766. [PDF]

Proc Int Astron Union, 2019
Roquette J, Bouvier J, Moraux E, Bouy H, Irwin J, Aigrain S, Lachaume R.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The 2D dynamics of radiative zones of low-mass stars

, 2018
Context. Helioseismology and asteroseismology allow us to probe the differential rotation deep within low-mass stars. In the solar convective envelope, the rotation varies with latitude with an equator rotating faster than the pole, which results in a ...
Mathis, Stéphane, D. Hypolite, S. Mathis, Hypolite, Delphine, Rieutord, Michel, M. Rieutord   +5 more
core   +1 more source

Measuring the magnetic fields in the chromospheres of low-mass stars [PDF]

Nat Commun
Cang T, Petit P, Donati J, Tian H, Fu J, Li H, Bellotti S, Hu X, Ma X, Ariste AL, Xing K, Morin J, Lu H, Zong W.   +13 more
europepmc   +2 more sources

Characterizing <i>K2</i> Candidate Planetary Systems Orbiting Low-Mass Stars IV: Updated Properties for 86 Cool Dwarfs Observed During Campaigns 1-17. [PDF]

Astrophys J, 2019
Dressing CD, Hardegree-Ullman K, Schlieder JE, Newton E, Vanderburg A, Feinstein AD, Duvvuri GM, Arnold L, Bristow M, Thackeray B, Abrahams ES, Ciardi D, Crossfield I, Yu L, Martinez AO, Christiansen JL, Crepp JR, Isaacson H.   +17 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source