Results 151 to 160 of about 55,137 (312)

The POKEMON Speckle Survey of Nearby M Dwarfs. III. The Stellar Multiplicity Rate of M Dwarfs within 15 pc

The Astronomical Journal
M dwarfs are ubiquitous in our Galaxy, and the rate at which they host stellar companions, and the properties of these companions, provide a window into the formation and evolution of the star(s), and of any planets that they may host.
Catherine A. Clark, Gerard T. van Belle, Elliott P. Horch, David R. Ciardi, Kaspar von Braun, Brian A. Skiff, Jennifer G. Winters, Michael B. Lund, Mark E. Everett, Zachary D. Hartman, Joe Llama   +10 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

New Ultracool Companions to Nearby White Dwarfs

The Astronomical Journal
We conducted a search for new ultracool companions to nearby white dwarfs using multiple methods, including the analysis of colors and examination of images in both the optical and the infrared.
Alexia Bravo, Adam C. Schneider, Sarah Casewell, Austin Rothermich, Jacqueline K. Faherty, Jenni R. French, Thomas P. Bickle, Aaron M. Meisner, J. Davy Kirkpatrick, Marc J. Kuchner, Adam J. Burgasser, Federico Marocco, John H. Debes, Arttu Sainio, Léopold Gramaize, Frank Kiwy, Peter A. Jałowiczor, Awab Abdullahi   +17 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Demographics of M Dwarf Binary Exoplanet Hosts Discovered by TESS

The Astronomical Journal
M dwarfs have become increasingly important in the detection of exoplanets and the study of Earth-sized planets and their habitability. However, 20%–30% of M dwarfs have companions that can impact the formation and evolution of planetary systems.
Rachel A. Matson, Rebecca Gore, Steve B. Howell, David R. Ciardi, Jessie L. Christiansen, Catherine A. Clark, Ian J. M. Crossfield, Sergio B. Fajardo-Acosta, Rachel B. Fernandes, Elise Furlan, Emily A. Gilbert, Erica Gonzales, Kathryn V. Lester, Michael B. Lund, Elisabeth C. Matthews, Alex S. Polanski, Joshua E. Schlieder, Carl Ziegler   +17 more
doaj   +1 more source

A fast method for deriving relative small-scale magnetic field variations from high-resolution spectroscopy

Astronomy & Astrophysics
Context. Setting observational constraints on stellar magnetic fields is essential for both stellar and planetary physics. They play a key role in the formation and evolution of stars and planets, and they are responsible for spurious signals in radial ...
Cristofari Paul I., Saar Steven H., Vidotto Aline A., Bellotti Stefano   +3 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Disk Lifetime Distribution as a Function of the Mass of Host Star

The Astrophysical Journal
The lifetime of protoplanetary disks is a critical factor for planet formation. Although the mean disk lifetime provides an estimate of the typical period available for planet formation, it does not capture the substantial variability in individual disk ...
Susanne Pfalzner, Furkan Dincer, Nienke van der Marel, Frank W. Wagner   +3 more
doaj   +1 more source

Pregalactic-primordial low-mass stars

, 1987
The Main-Sequence positions as well as the evolutionary behavior of Population III stars up to an evolution age of 2×1010 yr, taking this time as the age of the Universe, have been investigated in the mass range 0.2 and 0.8M ⊙. While Population III stars
Eryurt, Dilhan Ezer, Kızıloğlu, Nilgün Gülşan   +1 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source