Results 151 to 160 of about 1,262,170 (343)

Gravitational waves from low mass neutron stars [PDF]

Physical Review D, 2010
Low mass neutron stars may be uniquely strong sources of gravitational waves (GW). The neutron star crust can support large deformations for low mass stars. This is because of the star's weaker gravity. We find maximum ellipticities $ $ (fractional difference in moments of inertia) that are 1000 times larger, and maximum quadrupole moments $Q_{22 ...
openaire   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Realistic Uncertainties for Fundamental Properties of Asteroseismic Red Giants and the Interplay between Mixing Length, Metallicity, and

The Astrophysical Journal
Asteroseismic modeling is a powerful way to derive stellar properties. However, the derived quantities are limited by built-in assumptions used in stellar models.
Yaguang Li, Timothy R. Bedding, Daniel Huber, Dennis Stello, Jennifer van Saders, Yixiao Zhou, Courtney L. Crawford, Meridith Joyce, Tanda Li, Simon J. Murphy, K. R. Sreenivas   +10 more
doaj   +1 more source

Carbon-Enhanced Hyper-metal-poor Stars and the Stellar IMF at Low Metallicity

, 2007
The two known ``hyper-metal-poor'' (HMP) stars, HE0107-5240 and HE1327-2326, have extremely high enhancements of the light elements C, N, and O relative to Fe and appear to represent a statistically significant excess population relative to the halo ...
Duquennoy A., Jason Tumlinson, Wisotzki L.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Magnetic topologies of cool stars [PDF]

, 2007
Stellar magnetic fields can be investigated using several, very complementary approaches. While conventional spectroscopy is capable of estimating the average magnetic strength of potentially complex field configurations thanks to its low sensitivity to ...
Bouvier, J., Cameron, A. C., Delfosse, X., Dintrans, B., Dobler, W., Donati, J. -F., Dougados, C., Ferreira, J., Forveille, T., Gregory, S. G., Harries, T., Hussain, G. A. J., Jardine, M. M., Menard, F., Morin, J., Paletou, F., Petit, P.   +16 more
core   +1 more source

Mixed Phase in Compact Starts : M-R relations and radial oscillations

, 2003
It is believed that quark stars or neutron stars with mixed phase in the core have smaller radii compared to ordinary compact stars. With the recent observation of several low radius objects, typically a radius of $
Akaml A., ASHOK GOYAL, Chandrasekhar S., Drake J. J., Dutta B., Glendenning N. K., Glendenning N. K.   +6 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Stellar-Mass-Dependent Disk Structure in Coeval Planet-Forming Disks

, 2010
Previous studies suggest that the planet-forming disks around very-low-mass stars/brown dwarfs may be flatter than those around more massive stars, in contrast to model predictions of larger scale heights for gas-disks around lower-mass stars.
Andrews, Apai, Baraffe, Benz, Carpenter, Chiang, Cohen, Cornelis P. Dullemond, D'Alessio, Dániel Apai, Fazio, Furlan, Hartmann, Herczeg, Ida, Ilaria Pascucci, Johnson, Kennedy, Kessler-Silacci, Klein, Laughlin, Luhman, Luhman, Luhman, Luhman, László Szűcs, Mohanty, Muzerolle, Pascucci, Pascucci, Pascucci, Riaz, Riaz, Scholz, Skrutskie, Vetterling, Williams   +36 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source